Diverging targets mediate the pathological roleof miR-199a-5p and miR-199a-3p by promoting cardiac hypertrophy and fibrosis

MicroRNA-199a-5p (miR-199a-5p) and -3p are enriched in the myocardium, but it is unknown whether miR-199a-5p and -3p are co-expressed in cardiac remodeling and what roles they have in cardiac hypertrophy and fibrosis. We show that miR-199a-5p and -3p are co-upregulated in the mouse and human myocard...

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Detalles Bibliográficos
Autores principales: Zeng, Ni, Huang, Yu-Qing, Yan, Yu-Min, Hu, Zhi-Qin, Zhang, Zhuo, Feng, Jia-Xin, Guo, Ji-Shen, Zhu, Jie-Ning, Fu, Yong-Heng, Wang, Xi-Pei, Zhang, Meng-Zhen, Duan, Jin-Zhu, Zheng, Xi-Long, Xu, Jin-Dong, Shan, Zhi-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571541/
https://www.ncbi.nlm.nih.gov/pubmed/34786209
http://dx.doi.org/10.1016/j.omtn.2021.10.013

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