Cargando…

Aging whole blood transcriptome reveals candidate genes for SARS-CoV-2-related vascular and immune alterations

ABSTRACT: The risk of severe COVID-19 increases with age as older patients are at highest risk. Thus, there is an urgent need to identify how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) interacts with blood components during aging. We investigated the whole blood transcriptome from...

Descripción completa

Detalles Bibliográficos
Autores principales:	de Almeida Chuffa, Luiz Gustavo, Freire, Paula Paccielli, dos Santos Souza, Jeferson, de Mello, Mariana Costa, de Oliveira Neto, Mário, Carvalho, Robson Francisco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571664/ https://www.ncbi.nlm.nih.gov/pubmed/34741638 http://dx.doi.org/10.1007/s00109-021-02161-4

Ejemplares similares

The Transcriptomic Landscape of Age-Induced Changes in Human Visceral Fat and the Predicted Omentum-Liver Connectome in Males
por: de Moraes, Diogo, et al.
Publicado: (2023)

Low muscle mass in lung cancer is associated with an inflammatory and immunosuppressive tumor microenvironment
por: Cury, Sarah Santiloni, et al.
Publicado: (2023)

Tumor Transcriptome Reveals High Expression of IL-8 in Non-Small Cell Lung Cancer Patients with Low Pectoralis Muscle Area and Reduced Survival
por: Santiloni Cury, Sarah, et al.
Publicado: (2019)

The expression landscape of cachexia‐inducing factors in human cancers
por: Freire, Paula Paccielli, et al.
Publicado: (2020)

The authors reply: Comment on “The expression landscape of cachexia‐inducing factors in human cancers” by Freire et al.
por: Freire, Paula Paccielli, et al.
Publicado: (2020)

Maternal Protein Restriction Modulates Angiogenesis and AQP9 Expression Leading to a Delay in Postnatal Epididymal Development in Rat
por: de Mello Santos, Talita, et al.
Publicado: (2019)

Recovery of Cardiac Remodeling and Dysmetabolism by Pancreatic Islet Injury Improvement in Diabetic Rats after Yacon Leaf Extract Treatment
por: dos Santos, Klinsmann Carolo, et al.
Publicado: (2018)

The Pathway to Cancer Cachexia: MicroRNA-Regulated Networks in Muscle Wasting Based on Integrative Meta-Analysis
por: Freire, Paula Paccielli, et al.
Publicado: (2019)

Maternal Protein Restriction Alters the Expression of Proteins Related to the Structure and Functioning of the Rat Offspring Epididymis in an Age-Dependent Manner
por: Cavariani, Marilia Martins, et al.
Publicado: (2022)

Tumor Microenvironment Autophagic Processes and Cachexia: The Missing Link?
por: Gonçalves, Renata de Castro, et al.
Publicado: (2021)

Evaluation of Two Adjuvant Formulations for an Inactivated Yellow Fever 17DD Vaccine Candidate in Mice
por: Cajaraville, Ana Carolina dos Reis Albuquerque, et al.
Publicado: (2022)

An Integrated Meta-Analysis of Secretome and Proteome Identify Potential Biomarkers of Pancreatic Ductal Adenocarcinoma
por: de Oliveira, Grasieli, et al.
Publicado: (2020)

Maternal Protein Restriction Differentially Alters the Expression of AQP1, AQP9 and VEGFr-2 in the Epididymis of Rat Offspring
por: Cavariani, Marilia Martins, et al.
Publicado: (2019)

P-MAPA immunotherapy potentiates the effect of cisplatin on serous ovarian carcinoma through targeting TLR4 signaling
por: de Almeida Chuffa, Luiz Gustavo, et al.
Publicado: (2018)

Exosomes and Melatonin: Where Their Destinies Intersect
por: Novais, Adriana Alonso, et al.
Publicado: (2021)

Decoding Hidden Messengers: Proteomic Profiling of Exosomes in Mammary Cancer Research
por: Novais, Adriana Alonso, et al.
Publicado: (2023)

The Use of Herbal Medicine in Alzheimer's Disease—A Systematic Review
por: dos Santos-Neto, Leopoldo Luiz, et al.
Publicado: (2006)

Transcriptomic Response to Acidosis Reveals Its Contribution to Bone Metastasis in Breast Cancer Cells
por: Yamagata, Ana Sayuri, et al.
Publicado: (2022)

Melatonin Regulates the Daily Levels of Plasma Amino Acids, Acylcarnitines, Biogenic Amines, Sphingomyelins, and Hexoses in a Xenograft Model of Triple Negative Breast Cancer
por: Junior, Rubens Paula, et al.
Publicado: (2022)

Melatonin Promotes Uterine and Placental Health: Potential Molecular Mechanisms
por: de Almeida Chuffa, Luiz Gustavo, et al.
Publicado: (2019)

Melatonin and Pathological Cell Interactions: Mitochondrial Glucose Processing in Cancer Cells
por: Reiter, Russel J., et al.
Publicado: (2021)

Identification of NID1 as a novel candidate susceptibility gene for familial non-medullary thyroid carcinoma using whole-exome sequencing
por: de Mello, Luis Eduardo Barbalho, et al.
Publicado: (2021)

Potential Protective Role of Melatonin in Benign Mammary Cells Reprogrammed by Extracellular Vesicles from Malignant Cells
por: Procópio de Oliveira, Caroline, et al.
Publicado: (2023)

Whole-body transcriptome mining for candidate effectors from Diuraphis noxia
por: Nicolis, Vittorio F., et al.
Publicado: (2022)

Metabolic Alterations in Canine Mammary Tumors
por: Tamarindo, Guilherme Henrique, et al.
Publicado: (2023)

Aging-Related Ovarian Failure and Infertility: Melatonin to the Rescue
por: Reiter, Russel J., et al.
Publicado: (2023)

Prolonged fasting followed by refeeding modifies proteome profile and parvalbumin expression in the fast-twitch muscle of pacu (Piaractus mesopotamicus)
por: da Silva-Gomes, Rafaela Nunes, et al.
Publicado: (2019)

Melatonin Reverses the Warburg-Type Metabolism and Reduces Mitochondrial Membrane Potential of Ovarian Cancer Cells Independent of MT1 Receptor Activation
por: Cucielo, Maira Smaniotto, et al.
Publicado: (2022)

Horizontal Ridge Augmentation Using a Xenograft Bone Substitute for Implant-Supported Fixed Rehabilitation: A Case Report with Four Years of Follow-Up
por: Mello, Bruno Freitas, et al.
Publicado: (2020)

MicroRNA-mRNA Co-sequencing Identifies Transcriptional and Post-transcriptional Regulatory Networks Underlying Muscle Wasting in Cancer Cachexia
por: Fernandez, Geysson Javier, et al.
Publicado: (2020)

Potential Associations between Vascular Biology and Hodgkin’s Lymphoma: An Overview
por: Rodrigues, Wellington Francisco, et al.
Publicado: (2023)

Long-term sucrose solution consumption causes metabolic alterations and affects hepatic oxidative stress in Wistar rats
por: Souza Cruz, Ellen Mayara, et al.
Publicado: (2020)

A Redução do Colágeno Tipo I está Associada ao Aumento da Atividade da Metaloproteinase-2 e da Expressão Proteica de Leptina no Miocárdio de Ratos Obesos
por: da Silva-Bertani, Danielle Cristina Tomaz, et al.
Publicado: (2020)

Transcriptome Analysis Identifies ALCAM Overexpression as a Prognosis Biomarker in Laryngeal Squamous Cell Carcinoma
por: Nicolau-Neto, Pedro, et al.
Publicado: (2020)

Osteoglycin inhibition by microRNA miR-155 impairs myogenesis
por: Freire, Paula Paccielli, et al.
Publicado: (2017)

Temporizin and Temporizin-1 Peptides as Novel Candidates for Eliminating Trypanosoma cruzi
por: Souza, André L. A., et al.
Publicado: (2016)

Vascular mapping of the face: B-mode and doppler ultrasonography study
por: Tucunduva, Maria-José, et al.
Publicado: (2016)

Trichophyton rubrum dermatophytosis in a patient under chronic use of systemic corticoids: an exuberant presentation
por: Sena, Levi Bezerra, et al.
Publicado: (2015)

The Impact of Lung Carcinoma Histology on the Frequency of Bone Metastases
por: Oliveira, Marcelo Bragança dos Reis, et al.
Publicado: (2019)

P-MAPA and IL-12 Differentially Regulate Proteins Associated with Ovarian Cancer Progression: A Proteomic Study
por: Júnior, Luiz Antonio Lupi, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_5e4lvp19ggm4ricbr7dpcfvq1q