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Comprehensive insight into triclosan—from widespread occurrence to health outcomes
Humans are exposed to the variety of emerging environmental pollutant in everyday life. The special concern is paid to endocrine disrupting chemicals especially to triclosan which could interfere with normal hormonal functions. Triclosan could be found in numerous commercial products such as mouthwa...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571676/ https://www.ncbi.nlm.nih.gov/pubmed/34741734 http://dx.doi.org/10.1007/s11356-021-17273-0 |
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author | Milanović, Maja Đurić, Larisa Milošević, Nataša Milić, Nataša |
author_facet | Milanović, Maja Đurić, Larisa Milošević, Nataša Milić, Nataša |
author_sort | Milanović, Maja |
collection | PubMed |
description | Humans are exposed to the variety of emerging environmental pollutant in everyday life. The special concern is paid to endocrine disrupting chemicals especially to triclosan which could interfere with normal hormonal functions. Triclosan could be found in numerous commercial products such as mouthwashes, toothpastes and disinfectants due to its antibacterial and antifungal effects. Considering the excessive use and disposal, wastewaters are recognized as the main source of triclosan in the aquatic environment. As a result of the incomplete removal, triclosan residues reach surface water and even groundwater. Triclosan has potential to accumulate in sediment and aquatic organisms. Therefore, the detectable concentrations of triclosan in various environmental and biological matrices emerged concerns about the potential toxicity. Triclosan impairs thyroid homeostasis and could be associated with neurodevelopment impairment, metabolic disorders, cardiotoxicity and the increased cancer risk. The growing resistance of the vast groups of bacteria, the evidenced toxicity on different aquatic organisms, its adverse health effects observed in vitro, in vivo as well as the available epidemiological studies suggest that further efforts to monitor triclosan toxicity at environmental levels are necessary. The safety precaution measures and full commitment to proper legislation in compliance with the environmental protection are needed in order to obtain triclosan good ecological status. This paper is an overview of the possible negative triclosan effects on human health. Sources of exposure to triclosan, methods and levels of detection in aquatic environment are also discussed. |
format | Online Article Text |
id | pubmed-8571676 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-85716762021-11-08 Comprehensive insight into triclosan—from widespread occurrence to health outcomes Milanović, Maja Đurić, Larisa Milošević, Nataša Milić, Nataša Environ Sci Pollut Res Int Challenges in Managing and Risk Assessment of Emerging Environmental Pollutants Humans are exposed to the variety of emerging environmental pollutant in everyday life. The special concern is paid to endocrine disrupting chemicals especially to triclosan which could interfere with normal hormonal functions. Triclosan could be found in numerous commercial products such as mouthwashes, toothpastes and disinfectants due to its antibacterial and antifungal effects. Considering the excessive use and disposal, wastewaters are recognized as the main source of triclosan in the aquatic environment. As a result of the incomplete removal, triclosan residues reach surface water and even groundwater. Triclosan has potential to accumulate in sediment and aquatic organisms. Therefore, the detectable concentrations of triclosan in various environmental and biological matrices emerged concerns about the potential toxicity. Triclosan impairs thyroid homeostasis and could be associated with neurodevelopment impairment, metabolic disorders, cardiotoxicity and the increased cancer risk. The growing resistance of the vast groups of bacteria, the evidenced toxicity on different aquatic organisms, its adverse health effects observed in vitro, in vivo as well as the available epidemiological studies suggest that further efforts to monitor triclosan toxicity at environmental levels are necessary. The safety precaution measures and full commitment to proper legislation in compliance with the environmental protection are needed in order to obtain triclosan good ecological status. This paper is an overview of the possible negative triclosan effects on human health. Sources of exposure to triclosan, methods and levels of detection in aquatic environment are also discussed. Springer Berlin Heidelberg 2021-11-06 2023 /pmc/articles/PMC8571676/ /pubmed/34741734 http://dx.doi.org/10.1007/s11356-021-17273-0 Text en © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Challenges in Managing and Risk Assessment of Emerging Environmental Pollutants Milanović, Maja Đurić, Larisa Milošević, Nataša Milić, Nataša Comprehensive insight into triclosan—from widespread occurrence to health outcomes |
title | Comprehensive insight into triclosan—from widespread occurrence to health outcomes |
title_full | Comprehensive insight into triclosan—from widespread occurrence to health outcomes |
title_fullStr | Comprehensive insight into triclosan—from widespread occurrence to health outcomes |
title_full_unstemmed | Comprehensive insight into triclosan—from widespread occurrence to health outcomes |
title_short | Comprehensive insight into triclosan—from widespread occurrence to health outcomes |
title_sort | comprehensive insight into triclosan—from widespread occurrence to health outcomes |
topic | Challenges in Managing and Risk Assessment of Emerging Environmental Pollutants |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571676/ https://www.ncbi.nlm.nih.gov/pubmed/34741734 http://dx.doi.org/10.1007/s11356-021-17273-0 |
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