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CRISPR/Cas-Based Modifications for Therapeutic Applications: A Review

The CRISPR–Cas genome editing system is an intrinsic property of a bacteria-based immune system. This employs a guide RNA to detect and cleave the PAM-associated target DNA or RNA in subsequent infections, by the invasion of a similar bacteriophage. The discovery of Cas systems has paved the way to...

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Detalles Bibliográficos
Autores principales: Bharathkumar, Nagaraj, Sunil, Abraham, Meera, Prabhakar, Aksah, Sam, Kannan, Muthu, Saravanan, Konda Mani, Anand, Thirunavukarasou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571677/
https://www.ncbi.nlm.nih.gov/pubmed/34741732
http://dx.doi.org/10.1007/s12033-021-00422-8