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CRISPR/Cas-Based Modifications for Therapeutic Applications: A Review
The CRISPR–Cas genome editing system is an intrinsic property of a bacteria-based immune system. This employs a guide RNA to detect and cleave the PAM-associated target DNA or RNA in subsequent infections, by the invasion of a similar bacteriophage. The discovery of Cas systems has paved the way to...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571677/ https://www.ncbi.nlm.nih.gov/pubmed/34741732 http://dx.doi.org/10.1007/s12033-021-00422-8 |