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Prestimulation of CD2 confers resistance to HIV-1 latent infection in blood resting CD4 T cells

HIV-1 infects blood CD4 T cells through the use of CD4 and CXCR4 or CCR5 receptors, which can be targeted through blocking viral binding to CD4/CXCR4/CCR5 or virus-cell fusion. Here we describe a novel mechanism by which HIV-1 nuclear entry can also be blocked through targeting a non-entry receptor,...

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Detalles Bibliográficos
Autores principales: He, Sijia, Guo, Jia, Fu, Yajing, Spear, Mark, Qin, Chaolong, Fu, Shuai, Cui, Zongqiang, Jin, Wenwen, Xu, Xuehua, Chen, Wanjun, Shang, Hong, Wu, Yuntao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571718/
https://www.ncbi.nlm.nih.gov/pubmed/34765923
http://dx.doi.org/10.1016/j.isci.2021.103305