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Successful Treatment of Afatinib Reversing Epidermal Growth Factor Receptor Exon19Deletion/G724S Mutation Resistance Guided by Protein‐Drug Docking

G724S is a rare mutation induced by different generations of tyrosine kinase inhibitors (TKIs). No clinical effective drugs toward G724S mutation have been reported till now. We analyzed the interaction of three drugs (afatinib, gefitinib, osimertinib) with epidermal growth factor receptor (EGFR) fr...

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Detalles Bibliográficos
Autores principales:	Yu, Nian, Xu, Yinghui, Wang, Xu, Sun, Chao, Qiu, Shi, Guo, Ye, Bai, Miao, Huang, Yanxin, Ma, Kewei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2021
Materias:	Precision Medicine Clinic: Molecular Tumor Board
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571774/ https://www.ncbi.nlm.nih.gov/pubmed/34396638 http://dx.doi.org/10.1002/onco.13932

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