Carnosine quenches the reactive carbonyl acrolein in the central nervous system and attenuates autoimmune neuroinflammation

BACKGROUND: Multiple sclerosis (MS) is a chronic autoimmune disease driven by sustained inflammation in the central nervous system. One of the pathological hallmarks of MS is extensive free radical production. However, the subsequent generation, potential pathological role, and detoxification of dif...

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Detalles Bibliográficos
Autores principales: Spaas, Jan, Franssen, Wouter M. A., Keytsman, Charly, Blancquaert, Laura, Vanmierlo, Tim, Bogie, Jeroen, Broux, Bieke, Hellings, Niels, van Horssen, Jack, Posa, Dheeraj Kumar, Hoetker, David, Baba, Shahid P., Derave, Wim, Eijnde, Bert O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571880/
https://www.ncbi.nlm.nih.gov/pubmed/34740381
http://dx.doi.org/10.1186/s12974-021-02306-9

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