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Identification of Desmoglein-2 as a novel target of Helicobacter pylori HtrA in epithelial cells
BACKGROUND: High temperature requirement A (HtrA) is an active serine protease secreted by the group-I carcinogen Helicobacter pylori (H. pylori). The human cell adhesion protein and tumor suppressor E-cadherin (hCdh1) expressed on the surface of gastric epithelial cells was identified as the first...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571890/ https://www.ncbi.nlm.nih.gov/pubmed/34742300 http://dx.doi.org/10.1186/s12964-021-00788-x |