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Identification of Desmoglein-2 as a novel target of Helicobacter pylori HtrA in epithelial cells

BACKGROUND: High temperature requirement A (HtrA) is an active serine protease secreted by the group-I carcinogen Helicobacter pylori (H. pylori). The human cell adhesion protein and tumor suppressor E-cadherin (hCdh1) expressed on the surface of gastric epithelial cells was identified as the first...

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Detalles Bibliográficos
Autores principales: Bernegger, Sabine, Vidmar, Robert, Fonovic, Marko, Posselt, Gernot, Turk, Boris, Wessler, Silja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571890/
https://www.ncbi.nlm.nih.gov/pubmed/34742300
http://dx.doi.org/10.1186/s12964-021-00788-x

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