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Role of oncogenic KRAS in the prognosis, diagnosis and treatment of colorectal cancer

Colorectal cancer (CRC) is a heterogeneous disease at the cellular and molecular levels. Kirsten rat sarcoma (KRAS) is a commonly mutated oncogene in CRC, with mutations in approximately 40% of all CRC cases; its mutations result in constitutive activation of the KRAS protein, which acts as a molecu...

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Detalles Bibliográficos
Autores principales:	Zhu, Gongmin, Pei, Lijiao, Xia, Hongwei, Tang, Qiulin, Bi, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571891/ https://www.ncbi.nlm.nih.gov/pubmed/34742312 http://dx.doi.org/10.1186/s12943-021-01441-4

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