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MKL1 regulates hepatocellular carcinoma cell proliferation, migration and apoptosis via the COMPASS complex and NF-κB signaling

BACKGROUND: Histone modification plays essential roles in hepatocellular carcinoma (HCC) pathogenesis, but the regulatory mechanisms remain poorly understood. In this study, we aimed to analyze the roles of Megakaryoblastic leukemia 1 (MKL1) and its regulation of COMPASS (complex of proteins associa...

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Detalles Bibliográficos
Autores principales: Liu, Zhao, Sun, Jiuzheng, Li, Chuanzhi, Xu, Liyou, Liu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571910/
https://www.ncbi.nlm.nih.gov/pubmed/34742274
http://dx.doi.org/10.1186/s12885-021-08185-w