Cargando…

Large cell morphology, CMYC+ tumour cells, and PD-1+ tumour cell/intense PD-L1+ cell reactions are important prognostic factors in nodal peripheral T-cell lymphomas with T follicular helper markers

BACKGROUND: The clinicopathological characteristics and prognostic factors in nodal peripheral T-cell lymphomas (PTCLs) with two or more T follicular helper markers (TFH+) are not adequately investigated. METHODS: Immunohistologically, we selected 22 patients with TFH+ lymphoma (PTCL-TFH) in 47 of P...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mihashi, Yasuhito, Kimura, Shoichi, Iwasaki, Hiromi, Oshiro, Yumi, Takamatsu, Yasushi, Kawauchi, Shigeto, Shimajiri, Shohei, Ishizuka, Kenji, Takeshita, Morishige
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571911/ https://www.ncbi.nlm.nih.gov/pubmed/34742294 http://dx.doi.org/10.1186/s13000-021-01163-7

Ejemplares similares

Clinicopathological findings, prognosis, and Epstein–Barr virus infection in rheumatoid arthritis patients with other iatrogenic immunodeficiency-associated T- and NK-cell lymphoproliferative disorders
por: Kimura, Shoichi, et al.
Publicado: (2022)

Clinical and cytopathological characteristics of HTLV‐1(+) hodgkin lymphoma
por: Kobata, Katsumi, et al.
Publicado: (2020)

Conformance Assessment of PD-L1 Expression Between Primary Tumour and Nodal Metastases in Non-Small-Cell Lung Cancer
por: Xu, Haipeng, et al.
Publicado: (2019)

Endoscopic and clinicopathological characteristics of colorectal T/NK cell lymphoma
por: Ishibashi, Hideki, et al.
Publicado: (2020)

Anti-PD-1 antibody decreases tumour-infiltrating regulatory T cells
por: Yoshida, Kazushige, et al.
Publicado: (2020)

Tumour and host cell PD-L1 is required to mediate suppression of anti-tumour immunity in mice
por: Lau, Janet, et al.
Publicado: (2017)

PD-L1 expression patterns in tumour cells and their association with CD8(+) tumour infiltrating lymphocytes in clear cell renal cell carcinoma
por: Zhu, Qian, et al.
Publicado: (2019)

Benefit of prednisolone alone in nodal peripheral T-cell lymphoma with T follicular helper phenotype
por: Kitamura, Wataru, et al.
Publicado: (2023)

PD-1 Controls Follicular T Helper Cell Positioning and Function
por: Shi, Jingwen, et al.
Publicado: (2018)

Evaluation of PD-L1 expression on circulating tumour cells in small-cell lung cancer
por: Acheampong, Emmanuel, et al.
Publicado: (2022)

PD-L1 expressing circulating tumour cells in head and neck cancers
por: Kulasinghe, Arutha, et al.
Publicado: (2017)

Influence of Nodal signalling on pluripotency factor expression, tumour cell proliferation and cisplatin-sensitivity in testicular germ cell tumours
por: Harpelunde Poulsen, K., et al.
Publicado: (2020)

The mutational load and a T-cell inflamed tumour phenotype identify ovarian cancer patients rendering tumour-reactive T cells from PD-1(+) tumour-infiltrating lymphocytes
por: Salas-Benito, Diego, et al.
Publicado: (2021)

Elimination of acquired resistance to PD-1 blockade via the concurrent depletion of tumour cells and immunosuppressive cells
por: Xue, Gang, et al.
Publicado: (2021)

Erratum to evaluation of PD-L1 expression on circulating tumour cells in small cell lung cancer
Publicado: (2022)

Comparative evaluation of PD‐L1 expression in cytology imprints, circulating tumour cells and tumour tissue in non‐small cell lung cancer patients
por: Abdo, Mustafa, et al.
Publicado: (2023)

Pathologic and molecular insights in nodal T-follicular helper cell lymphomas
por: Marques-Piubelli, Mario L., et al.
Publicado: (2023)

cMyc increases cell number through uncoupling of cell division from cell size in CHO cells
por: Kuystermans, Darrin, et al.
Publicado: (2009)

PD-L1-specific helper T-cells exhibit effective antitumor responses: new strategy of cancer immunotherapy targeting PD-L1 in head and neck squamous cell carcinoma
por: Hirata-Nozaki, Yui, et al.
Publicado: (2019)

TGF-β attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells
por: Mariathasan, Sanjeev, et al.
Publicado: (2018)

The Immune Checkpoint PD-1 in Natural Killer Cells: Expression, Function and Targeting in Tumour Immunotherapy
por: Quatrini, Linda, et al.
Publicado: (2020)

CXCR5(+)PD-1(+) follicular helper CD8 T cells control B cell tolerance
por: Chen, Yuhong, et al.
Publicado: (2019)

Tumour cell‐intrinsic CTLA4 regulates PD‐L1 expression in non‐small cell lung cancer
por: Zhang, Huijun, et al.
Publicado: (2018)

PD-1 and TIGIT blockade differentially affect tumour cell survival under hypoxia and glucose deprived conditions in oesophageal adenocarcinoma; implications for overcoming resistance to PD-1 blockade in hypoxic tumours
por: Davern, Maria, et al.
Publicado: (2022)

TPF induction chemotherapy increases PD-L1 expression in tumour cells and immune cells in head and neck squamous cell carcinoma
por: Leduc, Charlotte, et al.
Publicado: (2018)

Follicular helper-T cells restore CD8(+)-dependent antitumor immunity and anti-PD-L1/PD-1 efficacy
por: Niogret, Julie, et al.
Publicado: (2021)

Clinical impact of tumour burden on the efficacy of PD‐1/PD‐L1 inhibitors plus chemotherapy in non‐small‐cell lung cancer
por: Miyawaki, Taichi, et al.
Publicado: (2022)

Dual role of tumour-infiltrating T helper 17 cells in human colorectal cancer
por: Amicarella, F, et al.
Publicado: (2017)

Transformation of normal cells by aberrant activation of YAP via cMyc with TEAD
por: Nishimoto, Masazumi, et al.
Publicado: (2019)

Spatial Profiles of Intratumoral PD-1(+) Helper T Cells Predict Prognosis in Head and Neck Squamous Cell Carcinoma
por: Yoshimura, Kanako, et al.
Publicado: (2021)

The prognostic value of PKM2 and its correlation with tumour cell PD-L1 in lung adenocarcinoma
por: Guo, Chang-Ying, et al.
Publicado: (2019)

Chrysin targets myeloid‐derived suppressor cells and enhances tumour response to anti‐PD‐1 immunotherapy
por: Li, Yinan, et al.
Publicado: (2022)

An Isolated Mesenteric Presentation of a Nodal Peripheral T Cell Lymphoma with T Follicular Helper Cell Phenotype
por: Keogh, Anna, et al.
Publicado: (2022)

PD-1 blockade restores helper activity of tumor-infiltrating, exhausted PD-1(hi)CD39(+) CD4 T cells
por: Balança, Camille-Charlotte, et al.
Publicado: (2021)

A novel multifunctional anti-PD-L1-CD16a-IL15 induces potent cancer cell killing in PD-L1-positive tumour cells
por: Li, Yumei, et al.
Publicado: (2022)

Circulating Exhausted PD-1(+)CD39(+) Helper CD4 T Cells Are Tumor-Antigen-Specific and Predict Response to PD-1/PD-L1 Axis Blockade
por: Martinez-Gomez, Carlos, et al.
Publicado: (2022)

Precise diagnosis and targeted therapy of nodal T-follicular helper cell lymphoma (T-FHCL)
por: Du, Jun, et al.
Publicado: (2023)

PD-1(+) CD8(+) T cells are exhausted in tumours and functional in draining lymph nodes of colorectal cancer patients
por: Wu, X, et al.
Publicado: (2014)

Tumour PD-L1 Expression in Small-Cell Lung Cancer: A Systematic Review and Meta-Analysis
por: Acheampong, Emmanuel, et al.
Publicado: (2020)

Loss of MYSM1 inhibits the oncogenic activity of cMYC in B cell lymphoma
por: Lin, Yun Hsiao, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_t4uqi9dlqn6a50c5m36iejbpu3