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YAP establishes epiblast responsiveness to inductive signals for germ cell fate

The germ cell lineage in mammals is induced by the stimulation of pluripotent epiblast cells by signaling molecules. Previous studies have suggested that the germ cell differentiation competence or responsiveness of epiblast cells to signaling molecules is established and maintained in epiblast cell...

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Detalles Bibliográficos
Autores principales: Kagiwada, Saya, Aramaki, Shinya, Wu, Guangming, Shin, Borami, Kutejova, Eva, Obridge, David, Adachi, Kenjiro, Wrana, Jeffrey L., Hübner, Karin, Schöler, Hans R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571999/
https://www.ncbi.nlm.nih.gov/pubmed/34528691
http://dx.doi.org/10.1242/dev.199732