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YAP establishes epiblast responsiveness to inductive signals for germ cell fate
The germ cell lineage in mammals is induced by the stimulation of pluripotent epiblast cells by signaling molecules. Previous studies have suggested that the germ cell differentiation competence or responsiveness of epiblast cells to signaling molecules is established and maintained in epiblast cell...
Autores principales: | Kagiwada, Saya, Aramaki, Shinya, Wu, Guangming, Shin, Borami, Kutejova, Eva, Obridge, David, Adachi, Kenjiro, Wrana, Jeffrey L., Hübner, Karin, Schöler, Hans R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571999/ https://www.ncbi.nlm.nih.gov/pubmed/34528691 http://dx.doi.org/10.1242/dev.199732 |
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