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Wnt/β-catenin signalling is dispensable for adult neural stem cell homeostasis and activation

Adult mouse hippocampal neural stem cells (NSCs) generate new neurons that integrate into existing hippocampal networks and modulate mood and memory. These NSCs are largely quiescent and are stimulated by niche signals to activate and produce neurons. Wnt/β-catenin signalling acts at different steps...

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Detalles Bibliográficos
Autores principales:	Austin, Sophie H. L., Gabarró-Solanas, Rut, Rigo, Piero, Paun, Oana, Harris, Lachlan, Guillemot, François, Urbán, Noelia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2021
Materias:	Stem Cells and Regeneration
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572000/ https://www.ncbi.nlm.nih.gov/pubmed/34557919 http://dx.doi.org/10.1242/dev.199629

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