Cargando…
Prevalence and Associated Factors of Kidney Dysfunction in Patients with Hypertension and/or Diabetes Mellitus from a Primary Care Population in Northwest China
PURPOSE: The burden of kidney dysfunction (KD) is rapidly increasing in developing countries due to an ongoing epidemic of hypertension and diabetes. We aimed to evaluate the prevalence and associated factors of KD among population with hypertension and/or diabetes from primary care setting. METHODS...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572047/ https://www.ncbi.nlm.nih.gov/pubmed/34754229 http://dx.doi.org/10.2147/IJGM.S329604 |
_version_ | 1784595146761830400 |
---|---|
author | Lin, Mengyue Heizhati, Mulalibieke Wang, Lin Gan, Lin Li, Mei Yang, Wenbo Yao, Ling Wang, Zhongrong Yang, Zhikang Abudoyreyimu, Reyila Wu, Zihao Li, Nanfang |
author_facet | Lin, Mengyue Heizhati, Mulalibieke Wang, Lin Gan, Lin Li, Mei Yang, Wenbo Yao, Ling Wang, Zhongrong Yang, Zhikang Abudoyreyimu, Reyila Wu, Zihao Li, Nanfang |
author_sort | Lin, Mengyue |
collection | PubMed |
description | PURPOSE: The burden of kidney dysfunction (KD) is rapidly increasing in developing countries due to an ongoing epidemic of hypertension and diabetes. We aimed to evaluate the prevalence and associated factors of KD among population with hypertension and/or diabetes from primary care setting. METHODS: This study was part of a cross-sectional study conducted in Northwest China, which aimed to investigate the epidemiological status of hypertension and other chronic noninfectious diseases. Subjects aged ≥18 years old with hypertension and/or diabetes were included in this study. KD was defined as estimated glomerular filtration rate (eGFR) less than 60 mL/min/1.73m(2). Least absolute shrinkage and selection operator and multivariable logistic regression were used to identify factors associated with KD. Sensitivity analysis was performed by comparing the results of different estimated equations for GFR. RESULTS: A total of 8899 participants with hypertension and/or diabetes were included. Prevalence of KD was 8.69% (n=144) among patients with both hypertension and DM, 3.36% (n=198) among patients with only hypertension, and 5.22% (n=70) among patients with only diabetes. Women showed higher prevalent KD than men. Modifiable factors independently associated with KD among patients with hypertension and/or diabetes included physical activity, duration of hypertension or DM, anemia, fasting plasma glucose and triglyceride. Results of different estimated equations showed similar trends of difference in the prevalence of KD among groups. CONCLUSION: KD is common in patients with hypertension and/or DM in Northwest China. More attention should be paid to high-risk patients, especially to those with co-existence of hypertension and DM. Control of blood glucose and triglyceride may further improve KD management in this patient population. |
format | Online Article Text |
id | pubmed-8572047 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-85720472021-11-08 Prevalence and Associated Factors of Kidney Dysfunction in Patients with Hypertension and/or Diabetes Mellitus from a Primary Care Population in Northwest China Lin, Mengyue Heizhati, Mulalibieke Wang, Lin Gan, Lin Li, Mei Yang, Wenbo Yao, Ling Wang, Zhongrong Yang, Zhikang Abudoyreyimu, Reyila Wu, Zihao Li, Nanfang Int J Gen Med Original Research PURPOSE: The burden of kidney dysfunction (KD) is rapidly increasing in developing countries due to an ongoing epidemic of hypertension and diabetes. We aimed to evaluate the prevalence and associated factors of KD among population with hypertension and/or diabetes from primary care setting. METHODS: This study was part of a cross-sectional study conducted in Northwest China, which aimed to investigate the epidemiological status of hypertension and other chronic noninfectious diseases. Subjects aged ≥18 years old with hypertension and/or diabetes were included in this study. KD was defined as estimated glomerular filtration rate (eGFR) less than 60 mL/min/1.73m(2). Least absolute shrinkage and selection operator and multivariable logistic regression were used to identify factors associated with KD. Sensitivity analysis was performed by comparing the results of different estimated equations for GFR. RESULTS: A total of 8899 participants with hypertension and/or diabetes were included. Prevalence of KD was 8.69% (n=144) among patients with both hypertension and DM, 3.36% (n=198) among patients with only hypertension, and 5.22% (n=70) among patients with only diabetes. Women showed higher prevalent KD than men. Modifiable factors independently associated with KD among patients with hypertension and/or diabetes included physical activity, duration of hypertension or DM, anemia, fasting plasma glucose and triglyceride. Results of different estimated equations showed similar trends of difference in the prevalence of KD among groups. CONCLUSION: KD is common in patients with hypertension and/or DM in Northwest China. More attention should be paid to high-risk patients, especially to those with co-existence of hypertension and DM. Control of blood glucose and triglyceride may further improve KD management in this patient population. Dove 2021-11-02 /pmc/articles/PMC8572047/ /pubmed/34754229 http://dx.doi.org/10.2147/IJGM.S329604 Text en © 2021 Lin et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Original Research Lin, Mengyue Heizhati, Mulalibieke Wang, Lin Gan, Lin Li, Mei Yang, Wenbo Yao, Ling Wang, Zhongrong Yang, Zhikang Abudoyreyimu, Reyila Wu, Zihao Li, Nanfang Prevalence and Associated Factors of Kidney Dysfunction in Patients with Hypertension and/or Diabetes Mellitus from a Primary Care Population in Northwest China |
title | Prevalence and Associated Factors of Kidney Dysfunction in Patients with Hypertension and/or Diabetes Mellitus from a Primary Care Population in Northwest China |
title_full | Prevalence and Associated Factors of Kidney Dysfunction in Patients with Hypertension and/or Diabetes Mellitus from a Primary Care Population in Northwest China |
title_fullStr | Prevalence and Associated Factors of Kidney Dysfunction in Patients with Hypertension and/or Diabetes Mellitus from a Primary Care Population in Northwest China |
title_full_unstemmed | Prevalence and Associated Factors of Kidney Dysfunction in Patients with Hypertension and/or Diabetes Mellitus from a Primary Care Population in Northwest China |
title_short | Prevalence and Associated Factors of Kidney Dysfunction in Patients with Hypertension and/or Diabetes Mellitus from a Primary Care Population in Northwest China |
title_sort | prevalence and associated factors of kidney dysfunction in patients with hypertension and/or diabetes mellitus from a primary care population in northwest china |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572047/ https://www.ncbi.nlm.nih.gov/pubmed/34754229 http://dx.doi.org/10.2147/IJGM.S329604 |
work_keys_str_mv | AT linmengyue prevalenceandassociatedfactorsofkidneydysfunctioninpatientswithhypertensionandordiabetesmellitusfromaprimarycarepopulationinnorthwestchina AT heizhatimulalibieke prevalenceandassociatedfactorsofkidneydysfunctioninpatientswithhypertensionandordiabetesmellitusfromaprimarycarepopulationinnorthwestchina AT wanglin prevalenceandassociatedfactorsofkidneydysfunctioninpatientswithhypertensionandordiabetesmellitusfromaprimarycarepopulationinnorthwestchina AT ganlin prevalenceandassociatedfactorsofkidneydysfunctioninpatientswithhypertensionandordiabetesmellitusfromaprimarycarepopulationinnorthwestchina AT limei prevalenceandassociatedfactorsofkidneydysfunctioninpatientswithhypertensionandordiabetesmellitusfromaprimarycarepopulationinnorthwestchina AT yangwenbo prevalenceandassociatedfactorsofkidneydysfunctioninpatientswithhypertensionandordiabetesmellitusfromaprimarycarepopulationinnorthwestchina AT yaoling prevalenceandassociatedfactorsofkidneydysfunctioninpatientswithhypertensionandordiabetesmellitusfromaprimarycarepopulationinnorthwestchina AT wangzhongrong prevalenceandassociatedfactorsofkidneydysfunctioninpatientswithhypertensionandordiabetesmellitusfromaprimarycarepopulationinnorthwestchina AT yangzhikang prevalenceandassociatedfactorsofkidneydysfunctioninpatientswithhypertensionandordiabetesmellitusfromaprimarycarepopulationinnorthwestchina AT abudoyreyimureyila prevalenceandassociatedfactorsofkidneydysfunctioninpatientswithhypertensionandordiabetesmellitusfromaprimarycarepopulationinnorthwestchina AT wuzihao prevalenceandassociatedfactorsofkidneydysfunctioninpatientswithhypertensionandordiabetesmellitusfromaprimarycarepopulationinnorthwestchina AT linanfang prevalenceandassociatedfactorsofkidneydysfunctioninpatientswithhypertensionandordiabetesmellitusfromaprimarycarepopulationinnorthwestchina |