Investigation of 1, 3, 4 Oxadiazole Derivative in PTZ-Induced Neurodegeneration: A Simulation and Molecular Approach

OBJECTIVE: The study investigated the effect 5-[(naphthalen-2-yloxy) methyl]-1,3,4-oxadiaszole2-thiol (B3) in animal model of acute epileptic shock. METHODS: The pharmacokinetics profile of B3 was checked through SwissADME software. The binding affinities of B3, diazepam, and flumazenil (FLZ) were o...

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Detalles Bibliográficos
Autores principales: Faheem, Muhammad, Althobaiti, Yusuf S, Khan, Abdul Waheed, Ullah, Aman, Ali, Syed Hussain, Ilyas, Umair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572052/
https://www.ncbi.nlm.nih.gov/pubmed/34754213
http://dx.doi.org/10.2147/JIR.S328609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572052/
https://www.ncbi.nlm.nih.gov/pubmed/34754213
http://dx.doi.org/10.2147/JIR.S328609

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