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Deep learning-based fully automated Z-axis coverage range definition from scout scans to eliminate overscanning in chest CT imaging

BACKGROUND: Despite the prevalence of chest CT in the clinic, concerns about unoptimized protocols delivering high radiation doses to patients still remain. This study aimed to assess the additional radiation dose associated with overscanning in chest CT and to develop an automated deep learning-ass...

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Autores principales: Salimi, Yazdan, Shiri, Isaac, Akhavanallaf, Azadeh, Mansouri, Zahra, Saberi Manesh, Abdollah, Sanaat, Amirhossein, Pakbin, Masoumeh, Askari, Dariush, Sandoughdaran, Saleh, Sharifipour, Ehsan, Arabi, Hossein, Zaidi, Habib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572075/
https://www.ncbi.nlm.nih.gov/pubmed/34743251
http://dx.doi.org/10.1186/s13244-021-01105-3
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author Salimi, Yazdan
Shiri, Isaac
Akhavanallaf, Azadeh
Mansouri, Zahra
Saberi Manesh, Abdollah
Sanaat, Amirhossein
Pakbin, Masoumeh
Askari, Dariush
Sandoughdaran, Saleh
Sharifipour, Ehsan
Arabi, Hossein
Zaidi, Habib
author_facet Salimi, Yazdan
Shiri, Isaac
Akhavanallaf, Azadeh
Mansouri, Zahra
Saberi Manesh, Abdollah
Sanaat, Amirhossein
Pakbin, Masoumeh
Askari, Dariush
Sandoughdaran, Saleh
Sharifipour, Ehsan
Arabi, Hossein
Zaidi, Habib
author_sort Salimi, Yazdan
collection PubMed
description BACKGROUND: Despite the prevalence of chest CT in the clinic, concerns about unoptimized protocols delivering high radiation doses to patients still remain. This study aimed to assess the additional radiation dose associated with overscanning in chest CT and to develop an automated deep learning-assisted scan range selection technique to reduce radiation dose to patients. RESULTS: A significant overscanning range (31 ± 24) mm was observed in clinical setting for over 95% of the cases. The average Dice coefficient for lung segmentation was 0.96 and 0.97 for anterior–posterior (AP) and lateral projections, respectively. By considering the exact lung coverage as the ground truth, and AP and lateral projections as input, The DL-based approach resulted in errors of 0.08 ± 1.46 and − 1.5 ± 4.1 mm in superior and inferior directions, respectively. In contrast, the error on external scout views was − 0.7 ± 4.08 and 0.01 ± 14.97 mm for superior and inferior directions, respectively.The ED reduction achieved by automated scan range selection was 21% in the test group. The evaluation of a large multi-centric chest CT dataset revealed unnecessary ED of more than 2 mSv per scan and 67% increase in the thyroid absorbed dose. CONCLUSION: The proposed DL-based solution outperformed previous automatic methods with acceptable accuracy, even in complicated and challenging cases. The generizability of the model was demonstrated by fine-tuning the model on AP scout views and achieving acceptable results. The method can reduce the unoptimized dose to patients by exclunding unnecessary organs from field of view. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13244-021-01105-3.
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spelling pubmed-85720752021-11-08 Deep learning-based fully automated Z-axis coverage range definition from scout scans to eliminate overscanning in chest CT imaging Salimi, Yazdan Shiri, Isaac Akhavanallaf, Azadeh Mansouri, Zahra Saberi Manesh, Abdollah Sanaat, Amirhossein Pakbin, Masoumeh Askari, Dariush Sandoughdaran, Saleh Sharifipour, Ehsan Arabi, Hossein Zaidi, Habib Insights Imaging Original Article BACKGROUND: Despite the prevalence of chest CT in the clinic, concerns about unoptimized protocols delivering high radiation doses to patients still remain. This study aimed to assess the additional radiation dose associated with overscanning in chest CT and to develop an automated deep learning-assisted scan range selection technique to reduce radiation dose to patients. RESULTS: A significant overscanning range (31 ± 24) mm was observed in clinical setting for over 95% of the cases. The average Dice coefficient for lung segmentation was 0.96 and 0.97 for anterior–posterior (AP) and lateral projections, respectively. By considering the exact lung coverage as the ground truth, and AP and lateral projections as input, The DL-based approach resulted in errors of 0.08 ± 1.46 and − 1.5 ± 4.1 mm in superior and inferior directions, respectively. In contrast, the error on external scout views was − 0.7 ± 4.08 and 0.01 ± 14.97 mm for superior and inferior directions, respectively.The ED reduction achieved by automated scan range selection was 21% in the test group. The evaluation of a large multi-centric chest CT dataset revealed unnecessary ED of more than 2 mSv per scan and 67% increase in the thyroid absorbed dose. CONCLUSION: The proposed DL-based solution outperformed previous automatic methods with acceptable accuracy, even in complicated and challenging cases. The generizability of the model was demonstrated by fine-tuning the model on AP scout views and achieving acceptable results. The method can reduce the unoptimized dose to patients by exclunding unnecessary organs from field of view. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13244-021-01105-3. Springer International Publishing 2021-11-06 /pmc/articles/PMC8572075/ /pubmed/34743251 http://dx.doi.org/10.1186/s13244-021-01105-3 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Salimi, Yazdan
Shiri, Isaac
Akhavanallaf, Azadeh
Mansouri, Zahra
Saberi Manesh, Abdollah
Sanaat, Amirhossein
Pakbin, Masoumeh
Askari, Dariush
Sandoughdaran, Saleh
Sharifipour, Ehsan
Arabi, Hossein
Zaidi, Habib
Deep learning-based fully automated Z-axis coverage range definition from scout scans to eliminate overscanning in chest CT imaging
title Deep learning-based fully automated Z-axis coverage range definition from scout scans to eliminate overscanning in chest CT imaging
title_full Deep learning-based fully automated Z-axis coverage range definition from scout scans to eliminate overscanning in chest CT imaging
title_fullStr Deep learning-based fully automated Z-axis coverage range definition from scout scans to eliminate overscanning in chest CT imaging
title_full_unstemmed Deep learning-based fully automated Z-axis coverage range definition from scout scans to eliminate overscanning in chest CT imaging
title_short Deep learning-based fully automated Z-axis coverage range definition from scout scans to eliminate overscanning in chest CT imaging
title_sort deep learning-based fully automated z-axis coverage range definition from scout scans to eliminate overscanning in chest ct imaging
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572075/
https://www.ncbi.nlm.nih.gov/pubmed/34743251
http://dx.doi.org/10.1186/s13244-021-01105-3
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