Pros and cons for the evidence of adaptive non-shivering thermogenesis in marsupials

The thermogenic mechanisms supporting endothermy are still not fully understood in all major mammalian subgroups. In placental mammals, brown adipose tissue currently represents the most accepted source of adaptive non-shivering thermogenesis. Its mitochondrial protein UCP1 (uncoupling protein 1) ca...

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Autores principales: Jastroch, Martin, Polymeropoulos, Elias T., Gaudry, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572181/
https://www.ncbi.nlm.nih.gov/pubmed/33860348
http://dx.doi.org/10.1007/s00360-021-01362-0
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author Jastroch, Martin
Polymeropoulos, Elias T.
Gaudry, Michael J.
author_facet Jastroch, Martin
Polymeropoulos, Elias T.
Gaudry, Michael J.
author_sort Jastroch, Martin
collection PubMed
description The thermogenic mechanisms supporting endothermy are still not fully understood in all major mammalian subgroups. In placental mammals, brown adipose tissue currently represents the most accepted source of adaptive non-shivering thermogenesis. Its mitochondrial protein UCP1 (uncoupling protein 1) catalyzes heat production, but the conservation of this mechanism is unclear in non-placental mammals and lost in some placentals. Here, we review the evidence for and against adaptive non-shivering thermogenesis in marsupials, which diverged from placentals about 120–160 million years ago. We critically discuss potential mechanisms that may be involved in the heat-generating process among marsupials.
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spelling pubmed-85721812021-11-15 Pros and cons for the evidence of adaptive non-shivering thermogenesis in marsupials Jastroch, Martin Polymeropoulos, Elias T. Gaudry, Michael J. J Comp Physiol B Review The thermogenic mechanisms supporting endothermy are still not fully understood in all major mammalian subgroups. In placental mammals, brown adipose tissue currently represents the most accepted source of adaptive non-shivering thermogenesis. Its mitochondrial protein UCP1 (uncoupling protein 1) catalyzes heat production, but the conservation of this mechanism is unclear in non-placental mammals and lost in some placentals. Here, we review the evidence for and against adaptive non-shivering thermogenesis in marsupials, which diverged from placentals about 120–160 million years ago. We critically discuss potential mechanisms that may be involved in the heat-generating process among marsupials. Springer Berlin Heidelberg 2021-04-15 2021 /pmc/articles/PMC8572181/ /pubmed/33860348 http://dx.doi.org/10.1007/s00360-021-01362-0 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review
Jastroch, Martin
Polymeropoulos, Elias T.
Gaudry, Michael J.
Pros and cons for the evidence of adaptive non-shivering thermogenesis in marsupials
title Pros and cons for the evidence of adaptive non-shivering thermogenesis in marsupials
title_full Pros and cons for the evidence of adaptive non-shivering thermogenesis in marsupials
title_fullStr Pros and cons for the evidence of adaptive non-shivering thermogenesis in marsupials
title_full_unstemmed Pros and cons for the evidence of adaptive non-shivering thermogenesis in marsupials
title_short Pros and cons for the evidence of adaptive non-shivering thermogenesis in marsupials
title_sort pros and cons for the evidence of adaptive non-shivering thermogenesis in marsupials
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572181/
https://www.ncbi.nlm.nih.gov/pubmed/33860348
http://dx.doi.org/10.1007/s00360-021-01362-0
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