Pharmacokinetics and Safety of Intravenous and Subcutaneous Auto-injector Single-dose Belimumab in Healthy Chinese Volunteers: A phase 1, Randomized, Open-label Study

INTRODUCTION: Belimumab is a recombinant human immunoglobulin G1λ monoclonal antibody indicated as an intravenous (IV) 10 mg/kg and subcutaneous (SC) 200-mg dose for the treatment of systemic lupus erythematosus (SLE). Belimumab 10 mg/kg IV has been approved for the treatment of patients with SLE in...

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Detalles Bibliográficos
Autores principales: Meng, Xianmin, Wang, Qianqian, Wu, Shunquan, Pu, Di, Zhang, Amber, Fang, Sun, Zhou, Xuan, Lu, Hongzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572285/
https://www.ncbi.nlm.nih.gov/pubmed/34554352
http://dx.doi.org/10.1007/s40744-021-00366-0

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