Cargando…

Characteristics of new adult users of mepolizumab with asthma in the USA

BACKGROUND: In the USA, over 25 million people have asthma; 5%–10% of cases are severe. Mepolizumab (Nucala) is an interleukin-5 antagonist monoclonal antibody; it was approved by the FDA in 2015 as add-on maintenance treatment of severe asthma for patients aged ≥12 years with an eosinophilic phenot...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Ann Chen, McMahon, Pamela M, Welch, Emily, McMahill-Walraven, Cheryl N, Jamal-Allial, Aziza, Gallagher, Mia, Zhang, Tancy, Draper, Christine, Kline, Anne Marie, Koerner, Leslie, Brown, Jeffrey S, Van Dyke, Melissa K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Asthma
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572414/ https://www.ncbi.nlm.nih.gov/pubmed/34732517 http://dx.doi.org/10.1136/bmjresp-2021-001003

Ejemplares similares

Patient characteristics, pain treatment patterns, and incidence of total joint replacement in a US population with osteoarthritis
por: Shinde, Mayura, et al.
Publicado: (2022)

Grandmaternal smoking, asthma and lung function in the offspring: the Lifelines cohort study
por: Mahon, Gillian M, et al.
Publicado: (2021)

Reslizumab as add-on therapy in patients with refractory asthma
por: Virchow, J Christian, et al.
Publicado: (2020)

Once-daily fluticasone furoate (FF)/vilanterol reduces risk of severe exacerbations in asthma versus FF alone
por: Bateman, Eric D, et al.
Publicado: (2014)

Safety and tolerability of the novel inhaled corticosteroid fluticasone furoate in combination with the β(2) agonist vilanterol administered once daily for 52 weeks in patients ≥12 years old with asthma: a randomised trial
por: Busse, William W, et al.
Publicado: (2013)

Three-month validation of a turbuhaler electronic monitoring device: implications for asthma clinical trial use
por: Pilcher, Janine, et al.
Publicado: (2015)

Phenotypic characteristics of asthma and morbidity are associated with distinct longitudinal changes in L-arginine metabolism
por: Althoff, Meghan Dolan, et al.
Publicado: (2023)

At-risk children with asthma (ARC): a systematic review
por: Buelo, Audrey, et al.
Publicado: (2018)

Lung function, airway and peripheral basophils and eosinophils are associated with molecular pharmacogenomic endotypes of steroid response in severe asthma
por: Kho, Alvin T, et al.
Publicado: (2022)

uPAR regulates bronchial epithelial repair in vitro and is elevated in asthmatic epithelium
por: Stewart, Ceri E, et al.
Publicado: (2011)

Risk factors for atopic and non-atopic asthma in a rural area of Ecuador
por: Moncayo, Ana Lucia, et al.
Publicado: (2010)

Refractory asthma in the UK: cross-sectional findings from a UK multicentre registry
por: Heaney, Liam G, et al.
Publicado: (2010)

Quantitative analysis of high-resolution computed tomography scans in severe asthma subphenotypes
por: Gupta, Sumit, et al.
Publicado: (2010)

Adverse effects of salmeterol in asthma: a neuronal perspective
por: Lommatzsch, M, et al.
Publicado: (2009)

Combination of budesonide/formoterol on demand improves asthma control by reducing exercise-induced bronchoconstriction
por: Lazarinis, Nikolaos, et al.
Publicado: (2014)

Tolerability in man following inhalation dosing of the selective TLR7 agonist, AZD8848
por: Delaney, Stephen, et al.
Publicado: (2016)

Economic analysis of temperature-controlled laminar airflow (TLA) for the treatment of patients with severe persistent allergic asthma
por: Brazier, Peter, et al.
Publicado: (2016)

Effects of body mass index, tobacco smoking, alcohol drinking and solid fuel use on the risk of asthma: Individual Participant Data (IPD) meta-analysis of 175 000 individuals from 51 nationally representative surveys
por: Patra, Jayadeep, et al.
Publicado: (2016)

Factors associated with relapse in adult patients discharged from the emergency department following acute asthma: a systematic review
por: Hill, Jesse, et al.
Publicado: (2017)

Step 4: stick or twist? A review of asthma therapy
por: Slater, Mariel G, et al.
Publicado: (2016)

What are the pros and cons of electronically monitoring inhaler use in asthma? A multistakeholder perspective
por: Howard, Sam, et al.
Publicado: (2016)

Differentiation of quantitative CT imaging phenotypes in asthma versus COPD
por: Choi, Sanghun, et al.
Publicado: (2017)

Sputum colour can identify patients with neutrophilic inflammation in asthma
por: Pabreja, Kavita, et al.
Publicado: (2017)

Healthcare resource use and costs of severe, uncontrolled eosinophilic asthma in the UK general population
por: Kerkhof, Marjan, et al.
Publicado: (2018)

Concordance of opinions between patients and physicians and their relationship with symptomatic control and future risk in patients with moderate–severe asthma
por: Crespo-Lessmann, Astrid, et al.
Publicado: (2017)

Description of the protocol for the PRACTICAL study: a randomised controlled trial of the efficacy and safety of ICS/LABA reliever therapy in asthma
por: Fingleton, James, et al.
Publicado: (2017)

Assessing the use of BreatheSmart® mobile technology in adult patients with asthma: a remote observational study
por: Melvin, Emilie, et al.
Publicado: (2017)

Chlamydia pneumoniae-induced tumour necrosis factor alpha responses are lower in children with asthma compared with non-asthma
por: Smith-Norowitz, Tamar Anne, et al.
Publicado: (2018)

Sex and intimacy in people with severe asthma: a qualitative study
por: Holmes, Leanne Jo, et al.
Publicado: (2019)

Gut microbiota relationships to lung function and adult asthma phenotype: a pilot study
por: Begley, Lesa, et al.
Publicado: (2018)

Genetic and observational evidence supports a causal role of sex hormones on the development of asthma
por: Arathimos, Ryan, et al.
Publicado: (2019)

Persistent variations in national asthma mortality, hospital admissions and prevalence by socioeconomic status and region in England
por: Gupta, Ramyani P, et al.
Publicado: (2018)

Novel pharmacist-led intervention secures the minimally important difference (MID) in Asthma Control Test (ACT) score: better outcomes for patients and the healthcare provider
por: Tinelli, Michela, et al.
Publicado: (2018)

Rural to urban migration is associated with increased prevalence of childhood wheeze in a Latin-American city
por: Rodriguez, Alejandro, et al.
Publicado: (2017)

Maternal history of miscarriages and measures of fertility in relation to childhood asthma
por: Magnus, Maria Christine, et al.
Publicado: (2019)

Smoking and lung function among adults with newly onset asthma
por: Jaakkola, Jouni J K, et al.
Publicado: (2019)

Influence of weight status in the response to Step-2 maintenance therapies in children with asthma
por: Longo, Cristina, et al.
Publicado: (2019)

Novel electronic adherence monitoring devices in children with asthma: a mixed-methods study
por: Makhecha, Sukeshi, et al.
Publicado: (2020)

Maintenance inhaler therapy preferences of patients with asthma or chronic obstructive pulmonary disease: a discrete choice experiment
por: Tervonen, Tommi, et al.
Publicado: (2020)

Asthma and all-cause mortality in children and young adults: a population-based study
por: Caffrey Osvald, Emma, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_2rkcem787h0up4rfm4m4q72fsf