Cargando…

A Deafness Associated Protein TMEM43 Interacts with KCNK3 (TASK-1) Two-pore Domain K(+) (K2P) Channel in the Cochlea

The TMEM43 has been studied in human diseases such as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5) and auditory neuropathy spectrum disorder (ANSD). In the heart, the p.(Ser358Leu) mutation has been shown to alter intercalated disc protein function and disturb beating rhythms. In t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jang, Minwoo Wendy, Kim, Tai Young, Sharma, Kushal, Kwon, Jea, Yi, Eunyoung, Lee, C. Justin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society for Brain and Neural Sciences 2021
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572660/ https://www.ncbi.nlm.nih.gov/pubmed/34737237 http://dx.doi.org/10.5607/en21028

Ejemplares similares

Effects of the ventilatory stimulant, doxapram on human TASK‐3 (KCNK9, K2P9.1) channels and TASK‐1 (KCNK3, K2P3.1) channels
por: Cunningham, Kevin P., et al.
Publicado: (2019)

Two pore domain potassium channels in cerebral ischemia: a focus on K(2P)9.1 (TASK3, KCNK9)
por: Ehling, Petra, et al.
Publicado: (2010)

Correction: Two pore domain potassium channels in cerebral ischemia: a focus on K2P9.1 (TASK3, KCNK9)
por: Ehling, Petra, et al.
Publicado: (2013)

Functional analysis of missense variants in the TRESK (KCNK18) K(+) channel
por: Andres-Enguix, Isabelle, et al.
Publicado: (2012)

Dominant-Negative Effect of a Missense Variant in the TASK-2 (KCNK5) K(+) Channel Associated with Balkan Endemic Nephropathy
por: Reed, Alan P., et al.
Publicado: (2016)

2-Aminoethoxydiphenyl borate activates the mechanically gated human KCNK channels KCNK 2 (TREK-1), KCNK 4 (TRAAK), and KCNK 10 (TREK-2)
por: Beltrán, Leopoldo, et al.
Publicado: (2013)

Correction: Dominant-Negative Effect of a Missense Variant in the TASK-2 (KCNK5) K(+) Channel Associated with Balkan Endemic Nephropathy
por: Reed, Alan P., et al.
Publicado: (2016)

A monoclonal antibody against KCNK9 K(+) channel extracellular domain inhibits tumour growth and metastasis
por: Sun, Han, et al.
Publicado: (2016)

Identification and characterization of two zebrafish Twik related potassium channels, Kcnk2a and Kcnk2b
por: Nasr, Nathalie, et al.
Publicado: (2018)

Background K(2P) Channels KCNK3/9/15 Limit the Budding of Cell Membrane-derived Vesicles
por: Huang, Daniel Tsung-Ning, et al.
Publicado: (2011)

Structural basis for ion selectivity in TMEM175 K(+) channels
por: Brunner, Janine D, et al.
Publicado: (2020)

Gating and selectivity mechanisms for the lysosomal K(+) channel TMEM175
por: Oh, SeCheol, et al.
Publicado: (2020)

Effect of 158 herbal remedies on human TRPV1 and the two-pore domain potassium channels KCNK2, 3 and 9
por: Herbrechter, Robin, et al.
Publicado: (2020)

Developmental Role of Anoctamin-1/TMEM16A in Ca(2+)-Dependent Volume Change in Supporting Cells of the Mouse Cochlea
por: Yi, Eunyoung, et al.
Publicado: (2013)

Effective pore size and radius of capture for K(+) ions in K-channels
por: Moldenhauer, Hans, et al.
Publicado: (2016)

Independent activation of distinct pores in dimeric TMEM16A channels
por: Jeng, Grace, et al.
Publicado: (2016)

Gating the pore of the calcium-activated chloride channel TMEM16A
por: Lam, Andy K. M., et al.
Publicado: (2021)

Gain and loss of TASK3 channel function and its regulation by novel variation cause KCNK9 imprinting syndrome
por: Cousin, Margot A., et al.
Publicado: (2022)

Low-voltage Activating K(+) Channels in Cochlear Afferent Nerve Fiber Dendrites
por: Sharma, Kushal, et al.
Publicado: (2022)

Opening and Closing of KcnkØ Potassium Leak Channels Is Tightly Regulated
por: Zilberberg, Noam, et al.
Publicado: (2000)

Mechanism of pore opening in the calcium-activated chloride channel TMEM16A
por: Lam, Andy K. M., et al.
Publicado: (2021)

KCNK10, a Tandem Pore Domain Potassium Channel, Is a Regulator of Mitotic Clonal Expansion during the Early Stage of Adipocyte Differentiation
por: Nishizuka, Makoto, et al.
Publicado: (2014)

Deficiency of the Two-Pore Potassium Channel KCNK9 Impairs Intestinal Epithelial Cell Survival and Aggravates Dextran Sodium Sulfate-Induced Colitis
por: Pfeuffer, Steffen, et al.
Publicado: (2022)

Na(+) Interaction with the Pore of Shaker B K(+) Channels: Zero and Low K(+) Conditions
por: Gómez-Lagunas, Froylán
Publicado: (2001)

Myometrial relaxation of mice via expression of two pore domain acid sensitive K(+) (TASK-2) channels
por: Kyeong, Kyu-Sang, et al.
Publicado: (2016)

Heterodimerization of two pore domain K(+) channel TASK1 and TALK2 in living heterologous expression systems
por: Suzuki, Yoshiaki, et al.
Publicado: (2017)

Identification and Characterization of TMEM119-Positive Cells in the Postnatal and Adult Murine Cochlea
por: Bassiouni, Mohamed, et al.
Publicado: (2023)

Identification of TMEM206 proteins as pore of PAORAC/ASOR acid-sensitive chloride channels
por: Ullrich, Florian, et al.
Publicado: (2019)

Inhibition mechanism of the chloride channel TMEM16A by the pore blocker 1PBC
por: Lam, Andy K. M., et al.
Publicado: (2022)

The Impact of Heterozygous KCNK3 Mutations Associated With Pulmonary Arterial Hypertension on Channel Function and Pharmacological Recovery
por: Bohnen, Michael S., et al.
Publicado: (2017)

Pharmacology and Surface Electrostatics of the K Channel Outer Pore Vestibule
por: Quinn, Claire C., et al.
Publicado: (2007)

The pore structure and gating mechanism of K2P channels
por: Piechotta, Paula L, et al.
Publicado: (2011)

Deafness Gene Expression Patterns in the Mouse Cochlea Found by Microarray Analysis
por: Yoshimura, Hidekane, et al.
Publicado: (2014)

Novel insights into K(+) selectivity from high resolution structures of an open K(+) channel pore
por: Ye, Sheng, et al.
Publicado: (2010)

TMEM30A is essential for hair cell polarity maintenance in postnatal mouse cochlea
por: Xing, Yazhi, et al.
Publicado: (2023)

KCNK5 channels mostly expressed in cochlear outer sulcus cells are indispensable for hearing
por: Cazals, Yves, et al.
Publicado: (2015)

TASK-2: a K(2P) K(+) channel with complex regulation and diverse physiological functions
por: Cid, L. Pablo, et al.
Publicado: (2013)

A nonsense TMEM43 variant leads to disruption of connexin-linked function and autosomal dominant auditory neuropathy spectrum disorder
por: Jang, Minwoo Wendy, et al.
Publicado: (2021)

Nonindependent K(+) Movement through the Pore in IRK1 Potassium Channels
por: Stampe, Per, et al.
Publicado: (1998)

K Channel Subconductance Levels Result from Heteromeric Pore Conformations
por: Chapman, Mark L., et al.
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_qqga0kv3rovmdfcorpjtkdhg53