Cargando…

Predicting the grades of Astragali radix using mass spectrometry-based metabolomics and machine learning

Astragali radix (AR, the dried root of Astragalus) is a popular herbal remedy in both China and the United States. The commercially available AR is commonly classified into premium graded (PG) and ungraded (UG) ones only according to the appearance. To uncover novel sensitive and specific markers fo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Xinyue, Nai, Jingxue, Guo, Huimin, Yang, Xuping, Deng, Xiaoying, Yuan, Xia, Hua, Yunfei, Tian, Yuan, Xu, Fengguo, Zhang, Zunjian, Huang, Yin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Xi'an Jiaotong University 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572717/ https://www.ncbi.nlm.nih.gov/pubmed/34765274 http://dx.doi.org/10.1016/j.jpha.2020.07.008

Ejemplares similares

Plasma Pharmacokinetics and Tissue Distribution of Doxorubicin in Rats following Treatment with Astragali Radix
por: Huang, Yin, et al.
Publicado: (2022)

A Systematic Review of Phytochemistry, Pharmacology and Pharmacokinetics on Astragali Radix: Implications for Astragali Radix as a Personalized Medicine
por: Guo, Zhenzhen, et al.
Publicado: (2019)

Evaluation of the Pharmaceutical Properties and Value of Astragali Radix
por: Gong, Amy G. W., et al.
Publicado: (2018)

Comparison of the Immunoregulatory Function of Different Constituents in Radix Astragali and Radix Hedysari
por: Liu, Jing, et al.
Publicado: (2010)

Genotoxicity Evaluation of an Ethanol Extract Mixture of Astragali Radix and Salviae miltiorrhizae Radix
por: Lee, Jin-Seok, et al.
Publicado: (2018)

Mechanism of Radix Astragali and Radix Salviae Miltiorrhizae Ameliorates Hypertensive Renal Damage
por: Hou, Guangjian, et al.
Publicado: (2021)

Astragali radix: could it be an adjuvant for oxaliplatin-induced neuropathy?
por: Di Cesare Mannelli, Lorenzo, et al.
Publicado: (2017)

Quasi-MS(n )identification of flavanone 7-glycoside isomers in Da Chengqi Tang by high performance liquid chromatography-tandem mass spectrometry
por: Xu, Fengguo, et al.
Publicado: (2009)

The combination of Radix Astragali and Radix Angelicae Sinensis attenuates the IFN-γ-induced immune destruction of hematopoiesis in bone marrow cells
por: Liu, Juan, et al.
Publicado: (2019)

Purification, Structural Analysis and Cardio-Protective Activity of Polysaccharides from Radix Astragali
por: Wang, Shilei, et al.
Publicado: (2023)

Protective effect of astragalosides from Radix Astragali on adriamycin-induced podocyte injury
por: Sai, Yi-Pa, et al.
Publicado: (2018)

The potential mechanism of Astragali Radix in the treatment of children with nephrotic syndrome
por: Wen, Xiaomin, et al.
Publicado: (2021)

Neuroprotective effect of Astragali Radix on cerebral infarction based on proteomics
por: Li, Ying, et al.
Publicado: (2023)

Residue of Chlormequat and Regulatory Effects on the Specialized Metabolites of Astragali Radix
por: Qin, Honghan, et al.
Publicado: (2023)

Metabolomics combined with network pharmacology exploration reveals the modulatory properties of Astragali Radix extract in the treatment of liver fibrosis
por: Wang, Dan, et al.
Publicado: (2019)

Potential Quality Evaluation Method for Radix Astragali Based on Sweetness Indicators
por: Li, Ke, et al.
Publicado: (2015)

Quality Markers for Astragali Radix and Its Products Based on Process Analysis
por: Dai, Yuntao, et al.
Publicado: (2020)

Retraction Note: Astragali radix: could it be an adjuvant for oxaliplatin-induced neuropathy?
por: Di Cesare Mannelli, Lorenzo, et al.
Publicado: (2023)

A Network Pharmacology Analysis to Explore the Effect of Astragali Radix-Radix Angelica Sinensis on Traumatic Brain Injury
por: Xie, Genggeng, et al.
Publicado: (2018)

Cysteine-Rich Peptide Fingerprinting as a General Method for Herbal Analysis to Differentiate Radix Astragali and Radix Hedysarum
por: Huang, Jiayi, et al.
Publicado: (2019)

Radix Astragali and Radix Angelicae Sinensis in the Treatment of Idiopathic Pulmonary Fibrosis: A Systematic Review and Meta-analysis
por: Zhang, Yufeng, et al.
Publicado: (2020)

Edematous Erythema at the Hands and Feet Probably Caused By the Traditional Herb “Radix Astragali”
por: Kogure, Toshiaki, et al.
Publicado: (2011)

Integrated Analysis for Identifying Radix Astragali and Its Adulterants Based on DNA Barcoding
por: Zheng, Sihao, et al.
Publicado: (2014)

Investigation of Chemomarkers of Astragali Radix of Different Ages and Geographical Origin by NMR Profiling
por: Zheng, Lu, et al.
Publicado: (2015)

An Integrated Strategy for Effective-Component Discovery of Astragali Radix in the Treatment of Lung Cancer
por: Yang, Bing, et al.
Publicado: (2021)

Study on the Mechanism of Radix Astragali against Renal Aging Based on Network Pharmacology
por: Zhang, Ziyuan, et al.
Publicado: (2022)

Network Pharmacology–Based Prediction and Pharmacological Validation of Effects of Astragali Radix on Acetaminophen-Induced Liver Injury
por: Peng, Yuan, et al.
Publicado: (2022)

RRLC-QTOF/MS-Based Metabolomics Reveal the Mechanism of Chemical Variations and Transformations of Astragali Radix as a Result of the Roasting Process
por: Li, Yang, et al.
Publicado: (2022)

The protective effects of different compatibility proportions of the couplet medicines for Astragali Radix and Angelica sinensis Radix on myocardial infarction injury
por: Chen, Lu, et al.
Publicado: (2020)

Chemical Analysis of Astragali Complanati Semen and Its Hypocholesterolemic Effect Using Serum Metabolomics Based on Gas Chromatography-Mass Spectrometry
por: Sham, Tung Ting, et al.
Publicado: (2017)

Profiling of components of rhizoma et radix polygoni cuspidati by high-performance liquid chromatography with ultraviolet diode-array detector and ion trap/time-of-flight mass spectrometric detection
por: Fu, Jinfeng, et al.
Publicado: (2015)

Protective Effect and Mechanisms of Radix Astragali Injection on the Intestinal Mucosa of Rats with Obstructive Jaundice
por: Xiping, Zhang, et al.
Publicado: (2010)

Polysaccharides from astragali radix restore chemical-induced blood vessel loss in zebrafish
por: Hu, Guang, et al.
Publicado: (2012)

Anti-atherosclerotic function of Astragali Radix extract: downregulation of adhesion molecules in vitro and in vivo
por: You, Yang, et al.
Publicado: (2012)

Radix Astragali Stimulates p38 MARK Phosphorylation in Pediatric Patients with β-Thalassemia
por: Lu, Zhuoming, et al.
Publicado: (2016)

Anticancer Effect of Radix Astragali on Cholangiocarcinoma In Vitro and Its Mechanism via Network Pharmacology
por: Wang, Yixiu, et al.
Publicado: (2020)

Hypoglycemic effect of Taraxacum officinale root extract and its synergism with Radix Astragali extract
por: Li, Jingwen, et al.
Publicado: (2021)

Effects of Physical Properties and Processing Methods on Astragaloside IV and Flavonoids Content in Astragali radix
por: Chien, Mei-Yin, et al.
Publicado: (2022)

Advances in Chemical Composition, Extraction Techniques, Analytical Methods, and Biological Activity of Astragali Radix
por: Chang, Xiangna, et al.
Publicado: (2022)

Predicting the anti-inflammatory mechanism of Radix Astragali using network pharmacology and molecular docking
por: Ren, Jianwei, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_peknllncv3nndefupv2otb28ft