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Intrarectal Xyloglucan Administration Reduces Disease Severity in the Dextran Sodium Sulfate Model of Mouse Colitis

BACKGROUND: The pathophysiology of inflammatory bowel diseases remains poorly understood and treatment remains suboptimal for many patients. We hypothesize that the inflammatory milieu secondarily prolongs the injury and attenuates healing. We propose primary or adjuvant therapy with biocompatible a...

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Detalles Bibliográficos
Autores principales: Ross, Edward A, Miller, Madelyn H, Pacheco, Allison, Willenberg, Alicia R, Tigno-Aranjuez, Justine T, Crawford, Kaitlyn E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572737/
https://www.ncbi.nlm.nih.gov/pubmed/34764666
http://dx.doi.org/10.2147/CEG.S325945