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MSC derived EV loaded with miRNA‐22 inhibits the inflammatory response and nerve function recovery after spinal cord injury in rats

Our previous research has found that miRNA‐22 can inhibit the occurrence of pyroptosis by targeting GSDMD and decrease the production and release of inflammatory factors. In consideration of the therapeutic effects of mesenchymal stem cells (MSCs), MSCs‐EV were loaded with miRNA‐22 (EV‐miRNA‐22) to...

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Detalles Bibliográficos
Autores principales: Sheng, Yongjia, Zhou, Xiaohong, Wang, Jin, Shen, Heping, Wu, Shasha, Guo, Weiqun, Yang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572783/
https://www.ncbi.nlm.nih.gov/pubmed/34609045
http://dx.doi.org/10.1111/jcmm.16965