H3K27me3 immunostaining is diagnostic and prognostic in diffuse gliomas with oligodendroglial or mixed oligoastrocytic morphology

Oligodendroglioma is defined by IDH mutation and 1p/19q codeletion. The latter is mutually exclusive to ATRX immunohistochemical loss and has been recently associated with the loss of H3K27me3 immunostaining. We aimed to assess the diagnostic and prognostic value of H3K27me3 immuno-expression in dif...

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Detalles Bibliográficos
Autores principales: Ammendola, Serena, Caldonazzi, Nicolò, Simbolo, Michele, Piredda, Maria Liliana, Brunelli, Matteo, Poliani, Pietro Luigi, Pinna, Giampietro, Sala, Francesco, Ghimenton, Claudio, Scarpa, Aldo, Barresi, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572829/
https://www.ncbi.nlm.nih.gov/pubmed/34165590
http://dx.doi.org/10.1007/s00428-021-03134-1

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