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Engineering a variant of IL-17RA with high binding affinity to IL-17A for optimized immunotherapy
Immunotherapy is one of the most recently used treatments for numerous cancer types and also some autoimmune and inflammatory diseases. One of the valuable targets for immunotherapy is Interleukin-17A (IL-17A) or its receptor (IL-17RA) because overexpression of IL-17A as a pro-inflammatory cytokine...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572878/ https://www.ncbi.nlm.nih.gov/pubmed/34765462 http://dx.doi.org/10.1016/j.btre.2021.e00682 |