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“Kambakutaisoto” and Emotional Instability Associated With Premenstrual Syndrome

Many women suffer from premenstrual syndrome (PMS), which can be considered a modern illness in this busy society; mental symptoms, such as irritability, often affect the surroundings and result in loss of self-confidence. The symptoms of PMS are diverse, and it is often difficult to treat psychiatr...

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Autores principales: Shiota, Atsuko, Shime, Chika, Nakai, Kyoko, Kageyama, Mitsuru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573044/
https://www.ncbi.nlm.nih.gov/pubmed/34760911
http://dx.doi.org/10.3389/fnut.2021.760958
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author Shiota, Atsuko
Shime, Chika
Nakai, Kyoko
Kageyama, Mitsuru
author_facet Shiota, Atsuko
Shime, Chika
Nakai, Kyoko
Kageyama, Mitsuru
author_sort Shiota, Atsuko
collection PubMed
description Many women suffer from premenstrual syndrome (PMS), which can be considered a modern illness in this busy society; mental symptoms, such as irritability, often affect the surroundings and result in loss of self-confidence. The symptoms of PMS are diverse, and it is often difficult to treat psychiatric and social symptoms with low-dose estrogen progestin combination drug (LEP) alone. Selective serotonin reuptake inhibitors (SSRIs) are also effective; however, many are unable to take them owing to their side effects. “Kambakutaisoto” is a Kampo medicine consisting of “jujube,” “licorice,” and “wheat,” which is often described as “food”; however, it is highly effective in treating emotional instability attributed to PMS in sensitive young women. There are many reports on the effects of kambakutaisoto; the molecular nutritional findings of kambakutaisoto, which has dramatic effects despite its mild composition of crude drugs, have also been reported, suggesting an association with premenstrual exacerbation of functional hypoglycemia. A narrative review of its clinical effects on PMS and the results of molecular nutrition studies was performed.
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spelling pubmed-85730442021-11-09 “Kambakutaisoto” and Emotional Instability Associated With Premenstrual Syndrome Shiota, Atsuko Shime, Chika Nakai, Kyoko Kageyama, Mitsuru Front Nutr Nutrition Many women suffer from premenstrual syndrome (PMS), which can be considered a modern illness in this busy society; mental symptoms, such as irritability, often affect the surroundings and result in loss of self-confidence. The symptoms of PMS are diverse, and it is often difficult to treat psychiatric and social symptoms with low-dose estrogen progestin combination drug (LEP) alone. Selective serotonin reuptake inhibitors (SSRIs) are also effective; however, many are unable to take them owing to their side effects. “Kambakutaisoto” is a Kampo medicine consisting of “jujube,” “licorice,” and “wheat,” which is often described as “food”; however, it is highly effective in treating emotional instability attributed to PMS in sensitive young women. There are many reports on the effects of kambakutaisoto; the molecular nutritional findings of kambakutaisoto, which has dramatic effects despite its mild composition of crude drugs, have also been reported, suggesting an association with premenstrual exacerbation of functional hypoglycemia. A narrative review of its clinical effects on PMS and the results of molecular nutrition studies was performed. Frontiers Media S.A. 2021-10-25 /pmc/articles/PMC8573044/ /pubmed/34760911 http://dx.doi.org/10.3389/fnut.2021.760958 Text en Copyright © 2021 Shiota, Shime, Nakai and Kageyama. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Nutrition
Shiota, Atsuko
Shime, Chika
Nakai, Kyoko
Kageyama, Mitsuru
“Kambakutaisoto” and Emotional Instability Associated With Premenstrual Syndrome
title “Kambakutaisoto” and Emotional Instability Associated With Premenstrual Syndrome
title_full “Kambakutaisoto” and Emotional Instability Associated With Premenstrual Syndrome
title_fullStr “Kambakutaisoto” and Emotional Instability Associated With Premenstrual Syndrome
title_full_unstemmed “Kambakutaisoto” and Emotional Instability Associated With Premenstrual Syndrome
title_short “Kambakutaisoto” and Emotional Instability Associated With Premenstrual Syndrome
title_sort “kambakutaisoto” and emotional instability associated with premenstrual syndrome
topic Nutrition
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573044/
https://www.ncbi.nlm.nih.gov/pubmed/34760911
http://dx.doi.org/10.3389/fnut.2021.760958
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