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Canonical and Non-canonical TGFβ Signaling Activate Autophagy in an ULK1-Dependent Manner

The mechanism(s) in which transforming growth factor beta 1 (TGFβ) modulates autophagy in cancer remain unclear. Here, we characterized the TGFβ signaling pathways that induce autophagy in non-small cell lung cancer cells, using cells lines stably expressing GFP-LC3-RFP-LC3ΔG constructs that measure...

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Detalles Bibliográficos
Autores principales:	Trelford, Charles B., Di Guglielmo, Gianni M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573198/ https://www.ncbi.nlm.nih.gov/pubmed/34760883 http://dx.doi.org/10.3389/fcell.2021.712124

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