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Fc Binding by FcγRIIa Is Essential for Cellular Activation by the Anti-FcγRIIa mAbs 8.26 and 8.2

FcγR activity underpins the role of antibodies in both protective immunity and auto-immunity and importantly, the therapeutic activity of many monoclonal antibody therapies. Some monoclonal anti-FcγR antibodies activate their receptors, but the properties required for cell activation are not well de...

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Detalles Bibliográficos
Autores principales:	Wines, Bruce D., Trist, Halina M., Esparon, Sandra, Impey, Rachael E., Mackay, Graham A., Andrews, Robert K., Soares da Costa, Tatiana P., Pietersz, Geoffrey A., Baker, Ross I., Hogarth, P. Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573391/ https://www.ncbi.nlm.nih.gov/pubmed/34759915 http://dx.doi.org/10.3389/fimmu.2021.666813

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