Cargando…
Evidence supporting a role for circulating macrophages in the regression of vascular remodeling following sub-chronic exposure to hemoglobin plus hypoxia
Macrophages are a heterogeneous population with both pro- and anti-inflammatory functions play an essential role in maintaining tissue homeostasis, promoting inflammation under pathological conditions, and tissue repair after injury. In pulmonary hypertension, the M1 phenotype is more pro-inflammato...
Autores principales: | Karoor, Vijaya, Swindle, Delaney, Pak, David I, Strassheim, Derek, Fini, Mehdi A, Dempsey, Edward, Stenmark, Kurt R, Hassell, Kathryn, Nuss, Rachelle, Buehler, Paul W., Irwin, David C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573496/ https://www.ncbi.nlm.nih.gov/pubmed/34777787 http://dx.doi.org/10.1177/20458940211056806 |
Ejemplares similares
-
Hemoglobin induced cell trauma indirectly influences endothelial TLR9 activity resulting in pulmonary vascular smooth muscle cell activation
por: Loomis, Zoe, et al.
Publicado: (2017) -
Correction: Hemoglobin induced cell trauma indirectly influences endothelial TLR9 activity resulting in pulmonary vascular smooth muscle cell activation
por: Loomis, Zoe, et al.
Publicado: (2017) -
RhoGTPase in Vascular Disease
por: Strassheim, Derek, et al.
Publicado: (2019) -
The Short-Chain Fatty Acid Butyrate Attenuates Pulmonary Vascular Remodeling and Inflammation in Hypoxia-Induced Pulmonary Hypertension
por: Karoor, Vijaya, et al.
Publicado: (2021) -
Murine models of sickle cell disease and beta-thalassemia demonstrate pulmonary hypertension with distinctive features
por: Buehler, Paul W., et al.
Publicado: (2021)