Glomerular endothelial cell senescence drives age‐related kidney disease through PAI‐1

The mechanisms underlying the development of glomerular lesions during aging are largely unknown. It has been suggested that senescence might play a role, but the pathophysiological link between senescence and lesion development remains unexplained. Here, we uncovered an unexpected role for glomerul...

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Detalles Bibliográficos
Autores principales: Cohen, Camille, Le Goff, Océane, Soysouvanh, Frédéric, Vasseur, Florence, Tanou, Marine, Nguyen, Clément, Amrouche, Lucile, Le Guen, Julien, Saltel‐Fulero, Oriana, Meunier, Tanguy, Nguyen‐Khoa, Thao, Rabant, Marion, Nochy, Dominique, Legendre, Christophe, Friedlander, Gérard, Childs, Bennett G, Baker, Daren J, Knebelmann, Bertrand, Anglicheau, Dany, Milliat, Fabien, Terzi, Fabiola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573606/
https://www.ncbi.nlm.nih.gov/pubmed/34725920
http://dx.doi.org/10.15252/emmm.202114146

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