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Brief survey on phytochemicals to prevent COVID-19

The recent pandemic by COVID-19 is a global threat to human health. The disease is caused by SARS-CoV-2 and the infection rate is increased more quickly than MERS and SARS as their rapid adaptation to varied climatic conditions through rapid mutations. It becomes more severe due to the lack of prope...

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Autores principales: Pal, Sanjoy, Chowdhury, Trinath, Paria, Kishalay, Manna, Sounik, Parveen, Sana, Singh, Manjeet, Sharma, Pralay, Islam, Sk Saruk, Abu Imam Saadi, Sk Md, Mandal, Santi M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Indian Chemical Society. Published by Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573676/
http://dx.doi.org/10.1016/j.jics.2021.100244
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author Pal, Sanjoy
Chowdhury, Trinath
Paria, Kishalay
Manna, Sounik
Parveen, Sana
Singh, Manjeet
Sharma, Pralay
Islam, Sk Saruk
Abu Imam Saadi, Sk Md
Mandal, Santi M.
author_facet Pal, Sanjoy
Chowdhury, Trinath
Paria, Kishalay
Manna, Sounik
Parveen, Sana
Singh, Manjeet
Sharma, Pralay
Islam, Sk Saruk
Abu Imam Saadi, Sk Md
Mandal, Santi M.
author_sort Pal, Sanjoy
collection PubMed
description The recent pandemic by COVID-19 is a global threat to human health. The disease is caused by SARS-CoV-2 and the infection rate is increased more quickly than MERS and SARS as their rapid adaptation to varied climatic conditions through rapid mutations. It becomes more severe due to the lack of proper therapeutic drugs, insufficient diagnostic tool, scarcity of appropriate drug, life supporting medical facility and mostly lack of awareness. Therefore, preventive measure is one of the important strategies to control. In this context, herbal medicinal plants received a noticeable attention to treat COVID-19 in Indian subcontinent. Here, 44 Indian traditional plants have been discussed with their novel phytochemicals that prevent the novel corona virus. The basic of SARS-CoV-2, their common way of transmission including their effect on immune and nervous system have been discussed. We have analysed their mechanism of action against COVID-19 following in-silico analysis. Their probable mechanism and therapeutic approaches behind the activity of phytochemicals to stimulate immune response as well as inhibition of viral multiplication discussed rationally. Thus, mixtures of active secondary metabolites/phytochemicals are the only choice to prevent the disease in countries where vaccination will take long time due to overcrowded population density.
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spelling pubmed-85736762021-11-08 Brief survey on phytochemicals to prevent COVID-19 Pal, Sanjoy Chowdhury, Trinath Paria, Kishalay Manna, Sounik Parveen, Sana Singh, Manjeet Sharma, Pralay Islam, Sk Saruk Abu Imam Saadi, Sk Md Mandal, Santi M. Journal of the Indian Chemical Society Article The recent pandemic by COVID-19 is a global threat to human health. The disease is caused by SARS-CoV-2 and the infection rate is increased more quickly than MERS and SARS as their rapid adaptation to varied climatic conditions through rapid mutations. It becomes more severe due to the lack of proper therapeutic drugs, insufficient diagnostic tool, scarcity of appropriate drug, life supporting medical facility and mostly lack of awareness. Therefore, preventive measure is one of the important strategies to control. In this context, herbal medicinal plants received a noticeable attention to treat COVID-19 in Indian subcontinent. Here, 44 Indian traditional plants have been discussed with their novel phytochemicals that prevent the novel corona virus. The basic of SARS-CoV-2, their common way of transmission including their effect on immune and nervous system have been discussed. We have analysed their mechanism of action against COVID-19 following in-silico analysis. Their probable mechanism and therapeutic approaches behind the activity of phytochemicals to stimulate immune response as well as inhibition of viral multiplication discussed rationally. Thus, mixtures of active secondary metabolites/phytochemicals are the only choice to prevent the disease in countries where vaccination will take long time due to overcrowded population density. Indian Chemical Society. Published by Elsevier B.V. 2022-01 2021-11-06 /pmc/articles/PMC8573676/ http://dx.doi.org/10.1016/j.jics.2021.100244 Text en © 2021 Indian Chemical Society. Published by Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Pal, Sanjoy
Chowdhury, Trinath
Paria, Kishalay
Manna, Sounik
Parveen, Sana
Singh, Manjeet
Sharma, Pralay
Islam, Sk Saruk
Abu Imam Saadi, Sk Md
Mandal, Santi M.
Brief survey on phytochemicals to prevent COVID-19
title Brief survey on phytochemicals to prevent COVID-19
title_full Brief survey on phytochemicals to prevent COVID-19
title_fullStr Brief survey on phytochemicals to prevent COVID-19
title_full_unstemmed Brief survey on phytochemicals to prevent COVID-19
title_short Brief survey on phytochemicals to prevent COVID-19
title_sort brief survey on phytochemicals to prevent covid-19
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573676/
http://dx.doi.org/10.1016/j.jics.2021.100244
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