Cargando…

A Review of Current Strategies Towards the Elimination of Latent HIV-1 and Subsequent HIV-1 Cure

BACKGROUND: During the past 35 years, highly effective ART has saved the lives of millions of people worldwide by suppressing viruses to undetectable levels. However, this does not translate to the absence of viruses in the body as HIV persists in latent reservoirs. Indeed, rebounded HIV has been re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Maina, Edward K., Adan, Asma A., Mureithi, Haddison, Muriuki, Joseph, Lwembe, Raphael M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573729/ https://www.ncbi.nlm.nih.gov/pubmed/32819259 http://dx.doi.org/10.2174/1570162X18999200819172009

Ejemplares similares

The Oncolytic Virus MG1 Targets and Eliminates Cells Latently Infected With HIV-1: Implications for an HIV Cure
por: Ranganath, Nischal, et al.
Publicado: (2018)

Efforts to eliminate the latent reservoir in resting CD4+ T cells: strategies for curing HIV-1 infection
por: Ho, Ya-Chi, et al.
Publicado: (2015)

Insights into the HIV-1 Latent Reservoir and Strategies to Cure HIV-1 Infection
por: Bai, Ruojing, et al.
Publicado: (2022)

Towards an HIV cure
por: Deeks, Steven
Publicado: (2014)

Specific Elimination of Latently HIV-1 Infected Cells Using HIV-1 Protease-Sensitive Toxin Nanocapsules
por: Wen, Jing, et al.
Publicado: (2016)

Targeting the latent reservoir to achieve functional HIV cure
por: Cary, Daniele C., et al.
Publicado: (2016)

Targeting Immune Checkpoint Molecules to Eliminate Latent HIV
por: Boyer, Zoe, et al.
Publicado: (2018)

HIV-1 subtype and viral tropism determination for evaluating antiretroviral therapy options: an analysis of archived Kenyan blood samples
por: Lihana, Raphael W, et al.
Publicado: (2009)

Trispecific antibody targeting HIV-1 and T cells activates and eliminates latently-infected cells in HIV/SHIV infections
por: Promsote, Wanwisa, et al.
Publicado: (2023)

Implications of HIV-1 Nef for “Shock and Kill” Strategies to Eliminate Latent Viral Reservoirs
por: Kuang, Xiaomei T., et al.
Publicado: (2018)

Block and Lock HIV Cure Strategies to Control the Latent Reservoir
por: Ahlenstiel, Chantelle L., et al.
Publicado: (2020)

Attacking latent HIV: towards eradication of HIV infection
por: Margolis, DM
Publicado: (2006)

Editorial: Exploring Novel Approaches to Eliminate HIV Reservoirs to Achieve a Cure for HIV
por: van der Sluis, Renée M., et al.
Publicado: (2021)

Editorial: Immunotherapies Towards HIV Cure
por: Salgado, Maria, et al.
Publicado: (2021)

Eliminating the latent HIV reservoir by reactivation strategies: Advancing to clinical trials
por: Rasmussen, Thomas A., et al.
Publicado: (2013)

Challenges in HIV-1 Latent Reservoir and Target Cell Quantification in CAR-T Cell and Other Lentiviral Gene Modifying HIV Cure Strategies
por: Buck, Amanda M., et al.
Publicado: (2023)

Human Papillomavirus Types Associated with Cervical Dysplasia among HIV- and Non-HIV-Infected Women Attending Reproductive Health Clinics in Eastern Kenya
por: Njue, James Kinoti, et al.
Publicado: (2021)

125 Progress Toward A Cure for HIV
por: Lafeuillade, Alain
Publicado: (2014)

Targeting the Brain Reservoirs: Toward an HIV Cure
por: Marban, Céline, et al.
Publicado: (2016)

Comparison of HIV-1 nef and gag Variations and Host HLA Characteristics as Determinants of Disease Progression among HIV-1 Vertically Infected Kenyan Children
por: Saina, Matilda Chelimo, et al.
Publicado: (2015)

Heterogeneity of HIV-1 latent reservoirs
por: Zhao, Jia-Cong, et al.
Publicado: (2020)

Strategies to eradicate HIV from infected patients: elimination of latent provirus reservoirs
por: Sadowski, Ivan, et al.
Publicado: (2019)

Towards a Functional Cure of HIV-1: Insight Into the Chromatin Landscape of the Provirus
por: Janssens, Julie, et al.
Publicado: (2021)

Crossroads of Cancer and HIV-1: Pathways to a Cure for HIV
por: Gavegnano, Christina, et al.
Publicado: (2019)

Modeling Kick-Kill Strategies toward HIV Cure
por: Hernandez-Vargas, Esteban A.
Publicado: (2017)

Anti-HIV-1 ADCC and HIV-1 Env Can Be Partners in Reducing Latent HIV Reservoir
por: Suryawanshi, Poonam, et al.
Publicado: (2021)

Protein Kinase C: One Pathway towards the Eradication of Latent HIV-1 Reservoirs
por: McKernan, Lisa N., et al.
Publicado: (2012)

Current Status of HIV-1 Vaccines
por: Hargrave, Anna, et al.
Publicado: (2021)

The current state of an HIV cure: innovative approaches and limitations
Publicado: (2019)

Broad activation of latent HIV-1 in vivo
por: Barton, Kirston, et al.
Publicado: (2016)

HIV-1 latent reservoir: size matters
por: Hodel, Flavia, et al.
Publicado: (2016)

Towards the next step: LoViRet patients for HIV-1 cure studies
por: Crespo, Raquel, et al.
Publicado: (2020)

Multimeric immunotherapeutic complexes activating natural killer cells towards HIV-1 cure
por: Schober, Rafaëla, et al.
Publicado: (2023)

Measuring the Success of HIV-1 Cure Strategies
por: Thomas, Jordan, et al.
Publicado: (2020)

Selective HDAC Inhibition for the Disruption of Latent HIV-1 Infection
por: Barton, Kirston M., et al.
Publicado: (2014)

Why the HIV Reservoir Never Runs Dry: Clonal Expansion and the Characteristics of HIV-Infected Cells Challenge Strategies to Cure and Control HIV Infection
por: Lau, Chuen-Yen, et al.
Publicado: (2021)

Antiretroviral (ARV) Drug Resistance and HIV-1 Subtypes among Injecting Drug Users in the Coastal Region of Kenya
por: Ng'ong'a, Gabriel O., et al.
Publicado: (2022)

An in vitro evaluation of drugs used in the Kenyan ART program
por: Muriuki, Joseph, et al.
Publicado: (2016)

Towards a cure for HIV: a long road ahead
por: Chun, Tae-Wook
Publicado: (2012)

Progress toward curing HIV infection with hematopoietic cell transplantation
por: Petz, Lawrence D, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_cen072ldsrthjqalu4gtr9i361