Pulmonary nodules associated with JAK inhibitor therapy in rheumatoid arthritis: A case report

Patients with rheumatoid arthritis (RA) may receive Janus kinase (JAK) inhibitors to achieve optimal control of their disease. We report a case of a patient who received a selective JAK1 inhibitor and subsequently developed multiple pulmonary nodules with cavitation. Biopsies confirmed the presence...

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Autores principales: Pannell, N, Joseph, D, Ally, M M T M, Bida, N M, Tintinger, G R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: South African Medical Association 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573811/
https://www.ncbi.nlm.nih.gov/pubmed/34761206
http://dx.doi.org/10.7196/AJTCCM.2021.v27i3.116
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author Pannell, N
Joseph, D
Ally, M M T M
Bida, N M
Tintinger, G R
author_facet Pannell, N
Joseph, D
Ally, M M T M
Bida, N M
Tintinger, G R
author_sort Pannell, N
collection PubMed
description Patients with rheumatoid arthritis (RA) may receive Janus kinase (JAK) inhibitors to achieve optimal control of their disease. We report a case of a patient who received a selective JAK1 inhibitor and subsequently developed multiple pulmonary nodules with cavitation. Biopsies confirmed the presence of cryptococcosis and the patient responded well to anti-fungal therapy.
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spelling pubmed-85738112021-11-09 Pulmonary nodules associated with JAK inhibitor therapy in rheumatoid arthritis: A case report Pannell, N Joseph, D Ally, M M T M Bida, N M Tintinger, G R Afr J Thorac Crit Care Med Case Report Patients with rheumatoid arthritis (RA) may receive Janus kinase (JAK) inhibitors to achieve optimal control of their disease. We report a case of a patient who received a selective JAK1 inhibitor and subsequently developed multiple pulmonary nodules with cavitation. Biopsies confirmed the presence of cryptococcosis and the patient responded well to anti-fungal therapy. South African Medical Association 2021-10-04 /pmc/articles/PMC8573811/ /pubmed/34761206 http://dx.doi.org/10.7196/AJTCCM.2021.v27i3.116 Text en https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution - NonCommercial Works License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Pannell, N
Joseph, D
Ally, M M T M
Bida, N M
Tintinger, G R
Pulmonary nodules associated with JAK inhibitor therapy in rheumatoid arthritis: A case report
title Pulmonary nodules associated with JAK inhibitor therapy in rheumatoid arthritis: A case report
title_full Pulmonary nodules associated with JAK inhibitor therapy in rheumatoid arthritis: A case report
title_fullStr Pulmonary nodules associated with JAK inhibitor therapy in rheumatoid arthritis: A case report
title_full_unstemmed Pulmonary nodules associated with JAK inhibitor therapy in rheumatoid arthritis: A case report
title_short Pulmonary nodules associated with JAK inhibitor therapy in rheumatoid arthritis: A case report
title_sort pulmonary nodules associated with jak inhibitor therapy in rheumatoid arthritis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573811/
https://www.ncbi.nlm.nih.gov/pubmed/34761206
http://dx.doi.org/10.7196/AJTCCM.2021.v27i3.116
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