Zinc protoporphyrin binding to telomerase complexes and inhibition of telomerase activity

Zinc protoporphyrin (ZnPP), a naturally occurring metalloprotoporphyrin (MPP), is currently under development as a chemotherapeutic agent although its mechanism is unclear. When tested against other MPPs, ZnPP was the most effective DNA synthesis and cellular proliferation inhibitor while promoting...

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Detalles Bibliográficos
Autores principales: Zhu, Zhaowen, Tran, Huy, Mathahs, Meleah M., Fink, Brian D., Albert, John A., Moninger, Thomas O., Meier, Jeffery L., Li, Ming, Schmidt, Warren N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573827/
https://www.ncbi.nlm.nih.gov/pubmed/34747573
http://dx.doi.org/10.1002/prp2.882

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