β-Carboline alkaloids induce structural plasticity and inhibition of SARS-CoV-2 nsp3 macrodomain more potently than remdesivir metabolite GS-441524: computational approach

The nsp3 macrodomain is implicated in the viral replication, pathogenesis and host immune responses through the removal of ADP-ribosylation sites during infections of coronaviruses including the SARS-CoV-2. It has ever been modulated by macromolecules including the ADP-ribose until Ni and co-workers...

Descripción completa

Detalles Bibliográficos
Autores principales: AYIPO, Yusuf Oloruntoyin, YAHAYA, Sani Najib, BABAMALE, Halimah Funmilayo, AHMAD, Iqrar, PATEL, Harun, MORDI, Mohd Nizam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific and Technological Research Council of Turkey 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573841/
https://www.ncbi.nlm.nih.gov/pubmed/34803450
http://dx.doi.org/10.3906/biy-2106-64

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573841/
https://www.ncbi.nlm.nih.gov/pubmed/34803450
http://dx.doi.org/10.3906/biy-2106-64

Ejemplares similares