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β-Carboline alkaloids induce structural plasticity and inhibition of SARS-CoV-2 nsp3 macrodomain more potently than remdesivir metabolite GS-441524: computational approach

The nsp3 macrodomain is implicated in the viral replication, pathogenesis and host immune responses through the removal of ADP-ribosylation sites during infections of coronaviruses including the SARS-CoV-2. It has ever been modulated by macromolecules including the ADP-ribose until Ni and co-workers...

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Detalles Bibliográficos
Autores principales:	AYIPO, Yusuf Oloruntoyin, YAHAYA, Sani Najib, BABAMALE, Halimah Funmilayo, AHMAD, Iqrar, PATEL, Harun, MORDI, Mohd Nizam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Scientific and Technological Research Council of Turkey 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573841/ https://www.ncbi.nlm.nih.gov/pubmed/34803450 http://dx.doi.org/10.3906/biy-2106-64

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