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Rab32 uses its effector reticulon 3L to trigger autophagic degradation of mitochondria-associated membrane (MAM) proteins
BACKGROUND: Rab32 is a small GTPase associated with multiple organelles but is particularly enriched at the endoplasmic reticulum (ER). Here, it controls targeting to mitochondria-ER contacts (MERCs), thus influencing composition of the mitochondria-associated membrane (MAM). Moreover, Rab32 regulat...
Autores principales: | Herrera-Cruz, Maria Sol, Yap, Megan C., Tahbaz, Nasser, Phillips, Keelie, Thomas, Laurel, Thomas, Gary, Simmen, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573869/ https://www.ncbi.nlm.nih.gov/pubmed/34743744 http://dx.doi.org/10.1186/s13062-021-00311-9 |
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