Drug triggered pruritus, rash, papules, and blisters – is AGEP a clash of an altered sphingolipid-metabolism and lysosomotropism of drugs accumulating in the skin?

Rash, photosensitivity, erythema multiforme, and the acute generalized exanthematous pustulosis (AGEP) are relatively uncommon adverse reactions of drugs. To date, the etiology is not well understood and individual susceptibility still remains unknown. Amiodarone, chlorpromazine, amitriptyline, and...

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Detalles Bibliográficos
Autores principales: Blaess, Markus, Kaiser, Lars, Sommerfeld, Oliver, Csuk, René, Deigner, Hans-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573906/
https://www.ncbi.nlm.nih.gov/pubmed/34743684
http://dx.doi.org/10.1186/s12944-021-01552-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573906/
https://www.ncbi.nlm.nih.gov/pubmed/34743684
http://dx.doi.org/10.1186/s12944-021-01552-3

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