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Silencing of UBE2D1 inhibited cell migration in gastric cancer, decreasing ubiquitination of SMAD4

BACKGROUND: Gastric cancer (GC) is the second leading cause of cancer-related deaths. Because it is hard to diagnose at early stage, the overall 5 years survival rate is lower than 25%. High migration is the main hallmark of malignant cells at advanced stage of GC. Thus, it is urgent to find biomark...

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Detalles Bibliográficos
Autores principales: Xie, Honghu, He, Yu, Wu, Yugang, Lu, Qicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8574036/
https://www.ncbi.nlm.nih.gov/pubmed/34743754
http://dx.doi.org/10.1186/s13027-021-00402-2