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Anti-metastatic effect of GV1001 on prostate cancer cells; roles of GnRHR-mediated Gαs-cAMP pathway and AR-YAP1 axis

BACKGROUND: Gonadotropin-releasing hormone receptor (GnRHR) transmits its signal via two major Gα-proteins, primarily Gαq and Gαi. However, the precise mechanism underlying the functions of Gαs signal in prostate cancer cells is still unclear. We have previously identified that GV1001, a fragment of...

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Detalles Bibliográficos
Autores principales:	Kim, Ji Won, Park, Miso, Kim, Suntae, Lim, Sung Chul, Kim, Hyung Shik, Kang, Keon Wook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8574053/ https://www.ncbi.nlm.nih.gov/pubmed/34743733 http://dx.doi.org/10.1186/s13578-021-00704-3

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