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CSF-resident CD4(+) T-cells display a distinct gene expression profile with relevance to immune surveillance and multiple sclerosis

The CNS has traditionally been considered an immune privileged site, but is now understood to have a system of immune surveillance, predominantly involving CD4(+) T-cells. Identifying functional differences between CNS and blood CD4(+) T-cells, therefore, have relevance to CNS immune surveillance as...

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Detalles Bibliográficos
Autores principales: Hrastelj, James, Andrews, Robert, Loveless, Samantha, Morgan, Joanne, Bishop, Stefan Mark, Bray, Nicholas J, Williams, Nigel M, Robertson, Neil P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8574295/
https://www.ncbi.nlm.nih.gov/pubmed/34761221
http://dx.doi.org/10.1093/braincomms/fcab155