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CSF-resident CD4(+) T-cells display a distinct gene expression profile with relevance to immune surveillance and multiple sclerosis
The CNS has traditionally been considered an immune privileged site, but is now understood to have a system of immune surveillance, predominantly involving CD4(+) T-cells. Identifying functional differences between CNS and blood CD4(+) T-cells, therefore, have relevance to CNS immune surveillance as...
Autores principales: | Hrastelj, James, Andrews, Robert, Loveless, Samantha, Morgan, Joanne, Bishop, Stefan Mark, Bray, Nicholas J, Williams, Nigel M, Robertson, Neil P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8574295/ https://www.ncbi.nlm.nih.gov/pubmed/34761221 http://dx.doi.org/10.1093/braincomms/fcab155 |
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