Cargando…

A multiple network-based bioinformatics pipeline for the study of molecular mechanisms in oncological diseases for personalized medicine

MOTIVATION: Assessment of genetic mutations is an essential element in the modern era of personalized cancer treatment. Our strategy is focused on ‘multiple network analysis’ in which we try to improve cancer diagnostics by using biological networks. Genetic alterations in some important hubs or in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dotolo, Serena, Marabotti, Anna, Rachiglio, Anna Maria, Esposito Abate, Riziero, Benedetto, Marco, Ciardiello, Fortunato, De Luca, Antonella, Normanno, Nicola, Facchiano, Angelo, Tagliaferri, Roberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Problem Solving Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8574709/ https://www.ncbi.nlm.nih.gov/pubmed/34050359 http://dx.doi.org/10.1093/bib/bbab180

Ejemplares similares

Bioinformatics: From NGS Data to Biological Complexity in Variant Detection and Oncological Clinical Practice
por: Dotolo, Serena, et al.
Publicado: (2022)

Community curation of bioinformatics software and data resources
por: Ison, Jon, et al.
Publicado: (2019)

PhosPiR: an automated phosphoproteomic pipeline in R
por: Hong, Ye, et al.
Publicado: (2021)

CRAFT: a bioinformatics software for custom prediction of circular RNA functions
por: Dal Molin, Anna, et al.
Publicado: (2022)

IBRAP: integrated benchmarking single-cell RNA-sequencing analytical pipeline
por: Knight, Connor H, et al.
Publicado: (2023)

ngsComposer: an automated pipeline for empirically based NGS data quality filtering
por: Kuster, Ryan D, et al.
Publicado: (2021)

NiPTUNE: an automated pipeline for noninvasive prenatal testing in an accurate, integrative and flexible framework
por: Duboc, Véronique, et al.
Publicado: (2021)

ChIP-AP: an integrated analysis pipeline for unbiased ChIP-seq analysis
por: Suryatenggara, Jeremiah, et al.
Publicado: (2021)

Bioinformatics mentorship in a resource limited setting
por: Jjingo, Daudi, et al.
Publicado: (2021)

MATTE: a pipeline of transcriptome module alignment for anti-noise phenotype-gene-related analysis
por: Cai, Guoxin, et al.
Publicado: (2023)

Improving artificial intelligence pipeline for liver malignancy diagnosis using ultrasound images and video frames
por: Xu, Yiming, et al.
Publicado: (2022)

GP(4): an integrated Gram-Positive Protein Prediction Pipeline for subcellular localization mimicking bacterial sorting
por: Grasso, Stefano, et al.
Publicado: (2020)

bulkAnalyseR: an accessible, interactive pipeline for analysing and sharing bulk multi-modal sequencing data
por: Moutsopoulos, Ilias, et al.
Publicado: (2022)

Minimal information for chemosensitivity assays (MICHA): a next-generation pipeline to enable the FAIRification of drug screening experiments
por: Tanoli, Ziaurrehman, et al.
Publicado: (2021)

TCRpower: quantifying the detection power of T-cell receptor sequencing with a novel computational pipeline calibrated by spike-in sequences
por: Dahal-Koirala, Shiva, et al.
Publicado: (2022)

Qmatey: an automated pipeline for fast exact matching-based alignment and strain-level taxonomic binning and profiling of metagenomes
por: Adams, Alison K, et al.
Publicado: (2023)

BindingSite-AugmentedDTA: enabling a next-generation pipeline for interpretable prediction models in drug repurposing
por: Yousefi, Niloofar, et al.
Publicado: (2023)

iWhale: a computational pipeline based on Docker and SCons for detection and annotation of somatic variants in cancer WES data
por: Binatti, Andrea, et al.
Publicado: (2020)

Validation of transcriptome signature reversion for drug repurposing in oncology
por: Koudijs, Karel K M, et al.
Publicado: (2022)

Virus-CKB: an integrated bioinformatics platform and analysis resource for COVID-19 research
por: Feng, Zhiwei, et al.
Publicado: (2020)

A novel bioinformatics approach to identify the consistently well-performing normalization strategy for current metabolomic studies
por: Yang, Qingxia, et al.
Publicado: (2019)

DLRAPom: a hybrid pipeline of Optimized XGBoost-guided integrative multiomics analysis for identifying targetable disease-related lncRNA–miRNA–mRNA regulatory axes
por: Shen, Chen, et al.
Publicado: (2022)

A new method to accurately identify single nucleotide variants using small FFPE breast samples
por: Fortunato, Angelo, et al.
Publicado: (2021)

Systematic investigation of the homology sequences around the human fusion gene breakpoints in pan-cancer – bioinformatics study for a potential link to MMEJ
por: Kim, Pora, et al.
Publicado: (2023)

Identification of viral-mediated pathogenic mechanisms in neurodegenerative diseases using network-based approaches
por: Onisiforou, Anna, et al.
Publicado: (2021)

Sensitive, reliable and robust circRNA detection from RNA-seq with CirComPara2
por: Gaffo, Enrico, et al.
Publicado: (2021)

binny: an automated binning algorithm to recover high-quality genomes from complex metagenomic datasets
por: Hickl, Oskar, et al.
Publicado: (2022)

Mutational signature assignment heterogeneity is widespread and can be addressed by ensemble approaches
por: Wu, Andy J, et al.
Publicado: (2023)

HLA3D: an integrated structure-based computational toolkit for immunotherapy
por: Li, Xingyu, et al.
Publicado: (2022)

Matching single cells across modalities with contrastive learning and optimal transport
por: Gossi, Federico, et al.
Publicado: (2023)

CODA: a combo-Seq data analysis workflow
por: Nazzari, Marta, et al.
Publicado: (2022)

Searching for Chymase Inhibitors among Chamomile Compounds Using a Computational-Based Approach
por: Dubey, Amit, et al.
Publicado: (2018)

Characterizing and explaining the impact of disease-associated mutations in proteins without known structures or structural homologs
por: Sen, Neeladri, et al.
Publicado: (2022)

Multi-omics data integration and network-based analysis drives a multiplex drug repurposing approach to a shortlist of candidate drugs against COVID-19
por: Tomazou, Marios, et al.
Publicado: (2021)

FGFR Fusions in Cancer: From Diagnostic Approaches to Therapeutic Intervention
por: De Luca, Antonella, et al.
Publicado: (2020)

A theoretical study on predicted protein targets of apple polyphenols and possible mechanisms of chemoprevention in colorectal cancer
por: Scafuri, Bernardina, et al.
Publicado: (2016)

Pleuritic Chest Pain; Where Should We Search for?
por: Gharib, Behdad, et al.
Publicado: (2011)

A young man with multiple joint pains and fever: A case with the importance of accurate history taking
por: Sonoda, Kento, et al.
Publicado: (2017)

A 16-year odyssey of cardiac sarcoid masquerading as idiopathic premature ventricular contractions and then arrhythmogenic cardiomyopathy
por: Nakamura, Tomofumi, et al.
Publicado: (2018)

Bundle branch reentry with His dissociation—The His bundle: Bystander or participant?
por: Nageh, Maged F., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_s5noj54f8230st10k6bigiaed6