SARS-CoV-2 Infection in an Adolescent With X-linked Agammaglobulinemia

We present a case of a 17-year-old boy with X-linked agammaglobulinemia who had mild disease when initially infected with SARS-CoV-2 but after recovering from acute infection developed fevers and a raised erythrocyte sedimentation rate that persisted for several weeks without any ongoing respiratory...

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Detalles Bibliográficos
Autores principales: Pereira, Noella Maria Delia, Heath, Paul T., Doerholt, Katja, Almario-Hernandez, Andres Fernando, Gilmour, Clare, Drysdale, Simon B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Immunology and Host Response
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575092/
https://www.ncbi.nlm.nih.gov/pubmed/34596628
http://dx.doi.org/10.1097/INF.0000000000003360
Descripción
Sumario:We present a case of a 17-year-old boy with X-linked agammaglobulinemia who had mild disease when initially infected with SARS-CoV-2 but after recovering from acute infection developed fevers and a raised erythrocyte sedimentation rate that persisted for several weeks without any ongoing respiratory symptoms. Multiple nasopharyngeal swabs were found to be negative for SARS-CoV-2 during the febrile period, but typical changes of COVID-19 on high resolution CT chest scan led to the detection of SARS-CoV-2 on RT-PCR in a sample from a bronchoalveolar lavage. His fevers completely resolved after a 5-day course of remdesivir.

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