SARS-CoV-2 Infection in an Adolescent With X-linked Agammaglobulinemia

We present a case of a 17-year-old boy with X-linked agammaglobulinemia who had mild disease when initially infected with SARS-CoV-2 but after recovering from acute infection developed fevers and a raised erythrocyte sedimentation rate that persisted for several weeks without any ongoing respiratory...

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Autores principales: Pereira, Noella Maria Delia, Heath, Paul T., Doerholt, Katja, Almario-Hernandez, Andres Fernando, Gilmour, Clare, Drysdale, Simon B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Immunology and Host Response
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575092/
https://www.ncbi.nlm.nih.gov/pubmed/34596628
http://dx.doi.org/10.1097/INF.0000000000003360
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author Pereira, Noella Maria Delia
Heath, Paul T.
Doerholt, Katja
Almario-Hernandez, Andres Fernando
Gilmour, Clare
Drysdale, Simon B.
author_facet Pereira, Noella Maria Delia
Heath, Paul T.
Doerholt, Katja
Almario-Hernandez, Andres Fernando
Gilmour, Clare
Drysdale, Simon B.
author_sort Pereira, Noella Maria Delia
collection PubMed
description We present a case of a 17-year-old boy with X-linked agammaglobulinemia who had mild disease when initially infected with SARS-CoV-2 but after recovering from acute infection developed fevers and a raised erythrocyte sedimentation rate that persisted for several weeks without any ongoing respiratory symptoms. Multiple nasopharyngeal swabs were found to be negative for SARS-CoV-2 during the febrile period, but typical changes of COVID-19 on high resolution CT chest scan led to the detection of SARS-CoV-2 on RT-PCR in a sample from a bronchoalveolar lavage. His fevers completely resolved after a 5-day course of remdesivir.
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spelling pubmed-85750922021-11-08 SARS-CoV-2 Infection in an Adolescent With X-linked Agammaglobulinemia Pereira, Noella Maria Delia Heath, Paul T. Doerholt, Katja Almario-Hernandez, Andres Fernando Gilmour, Clare Drysdale, Simon B. Pediatr Infect Dis J Immunology and Host Response We present a case of a 17-year-old boy with X-linked agammaglobulinemia who had mild disease when initially infected with SARS-CoV-2 but after recovering from acute infection developed fevers and a raised erythrocyte sedimentation rate that persisted for several weeks without any ongoing respiratory symptoms. Multiple nasopharyngeal swabs were found to be negative for SARS-CoV-2 during the febrile period, but typical changes of COVID-19 on high resolution CT chest scan led to the detection of SARS-CoV-2 on RT-PCR in a sample from a bronchoalveolar lavage. His fevers completely resolved after a 5-day course of remdesivir. Lippincott Williams & Wilkins 2021-11-08 2021-12 /pmc/articles/PMC8575092/ /pubmed/34596628 http://dx.doi.org/10.1097/INF.0000000000003360 Text en Copyright © 2021 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Immunology and Host Response
Pereira, Noella Maria Delia
Heath, Paul T.
Doerholt, Katja
Almario-Hernandez, Andres Fernando
Gilmour, Clare
Drysdale, Simon B.
SARS-CoV-2 Infection in an Adolescent With X-linked Agammaglobulinemia
title SARS-CoV-2 Infection in an Adolescent With X-linked Agammaglobulinemia
title_full SARS-CoV-2 Infection in an Adolescent With X-linked Agammaglobulinemia
title_fullStr SARS-CoV-2 Infection in an Adolescent With X-linked Agammaglobulinemia
title_full_unstemmed SARS-CoV-2 Infection in an Adolescent With X-linked Agammaglobulinemia
title_short SARS-CoV-2 Infection in an Adolescent With X-linked Agammaglobulinemia
title_sort sars-cov-2 infection in an adolescent with x-linked agammaglobulinemia
topic Immunology and Host Response
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575092/
https://www.ncbi.nlm.nih.gov/pubmed/34596628
http://dx.doi.org/10.1097/INF.0000000000003360
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