Camel nanobodies broadly neutralize SARS-CoV-2 variants

With the emergence of SARS-CoV-2 variants, there is urgent need to develop broadly neutralizing antibodies. Here, we isolate two VHH nanobodies (7A3 and 8A2) from dromedary camels by phage display, which have high affinity for the receptor-binding domain (RBD) and broad neutralization activities aga...

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Detalles Bibliográficos
Autores principales: Hong, Jessica, Kwon, Hyung Joon, Cachau, Raul, Chen, Catherine Z., Butay, Kevin John, Duan, Zhijian, Li, Dan, Ren, Hua, Liang, Tianyuzhou, Zhu, Jianghai, Dandey, Venkata P., Martin, Negin, Esposito, Dominic, Ortega-Rodriguez, Uriel, Xu, Miao, Borgnia, Mario J., Xie, Hang, Ho, Mitchell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575140/
https://www.ncbi.nlm.nih.gov/pubmed/34751270
http://dx.doi.org/10.1101/2021.10.27.465996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575140/
https://www.ncbi.nlm.nih.gov/pubmed/34751270
http://dx.doi.org/10.1101/2021.10.27.465996

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