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Definitions and elements of endpoints in phase III randomized trials for the treatment of COVID-19: a cross-sectional analysis of trials registered in ClinicalTrials.gov

BACKGROUND: There are several challenges in designing clinical trials for the treatment of novel infectious diseases, such as COVID-19. In particular, the definition of endpoints related to the severity, time frame, and clinical course remains unclear. Therefore, we conducted a cross-sectional analy...

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Detalles Bibliográficos
Autores principales: Sakamaki, Kentaro, Uemura, Yukari, Shimizu, Yosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8575152/
https://www.ncbi.nlm.nih.gov/pubmed/34749761
http://dx.doi.org/10.1186/s13063-021-05763-y